Search
Understanding the interplay between genomic Structural Variations and Phenotypes using the yeast model
Understanding the genetic determinants of phenotypic variation is a major challenge in modern biology. The complexity of the genetic architecture controlling the traits varies from Mendelian inheritan
Understanding the importance of gut microbiota for the improvement of swine efficiency and robustness
MICROFEED will study a generally ignored partner of livestock, the gut microbiota, to refund the improvement of production efficiency and robustness in pig breeding. The gut microbiota is an essential
Understanding spontaneous somatic mutations and their effects on adult tissues
During aging, defects in stem cell function contribute to a decline in renewal and repair of adult tissues. It has long been postulated that the accumulation of somatic mutations might contribute to c
Understanding cellular variation of 3D genome organization using novel Nanopore-sequencing-based Chromosome Conformation Capture assays.
Below, my abstract as provided in my ERC-StG project is provided: To understand the mechanisms of gene transcription and regulation, the essential functions of tridimensional (3D) genome organizati
Understanding assembly of macromolecular complexes using C/D snoRNPs as a model
Many cellular functions are performed by molecular machines made of RNA-protein complexes. For the cell, producing these RNP particles in a functional state can be a real challenge. Assembling RNP particles require factors that can chaperone free subunits, increase the specificity, transport subunits, and control the quality of the particle. The HSP90/R2TP is a chaperone specialized in quaterning folding. Our aim is to decipher its mechanisms of action using box C/D snoRNP as a model.
Understanding and exploiting endophytic nitrogen fixation for sustainable maize production
Maize farming requires high amounts of N fertilizer, with adverse environmental effects and insufficient agronomic sustainability. Certain maize genotypes can be colonized endophytically by atmospheri
Understanding and Managing Urban Ectomycorrhizal Fungi Communities to Increase the Health and Ecosystem Service Provisioning of Urban Trees
As 80% of the EU population is expected to live in urban areas by 2020, the quality of the urban environment is of growing importance. Urban trees are key elements in mitigating the common environment
Understanding and Controlling the Molybdenum Cofactor Reactivity in Enzymes and Maquette Proteins
Molybdenum and tungsten enzymes are present in most living organisms where they catalyze a wide diversity of reactions. They play essential roles in many metabolic processes of carbon, nitrogen, sulfu