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Mitochondrial transport mechanism at the molecular level
Mitochondria are cellular organelles responsible for the production of ATP, the chemical fuel of the cell. Several metabolic cycles occur within this compartment. The function of this organelle necessitates the exchange of several types of metabolites and small molecules between the mitochondrial matrix and the cytoplasm. The project aims at understanding the transport mechanisms at a molecular level, more specifically the role of essential membrane proteins, the mitochondrial carriers.
Recognition of hIstorical Chinese mAnuscripts
Recognition of historical Chinese manuscripts
Towards coherent radiation produced by particule beam accelerators injected with external lasers
In accelerator-based systems, a strategy for producing coherent radiation consists of injecting external laser pulses on a relativistic electron bunch. The resulting shaping of the electrons (bunchi
A parasite enzyme as a new therapeutic agent in Inflammatory Bowel Diseases
The present project (ACROHNEM: Anti CROHN Enzymatic Molecule) aims at the development of a well- characterized parasite protein as a new therapeutic agent in dramatically increasing Inflammatory Bowe
60 000 SNP chip to fine map QTL affecting production traits, resistance to diseases and behaviour in sheep.
During the last 15 years in France, 10 different QTL studies have been carried out in sheep. Numerous economically important traits (milk and meat production and/or quality, reproduction, behaviour an
Activity-dependent and independent mechanisms of visual map formation
This project aims to understand how connections from the eye to the brain are established to ensure a proper visual representation of the external world.
Adaptable, configurable and upgradable tool for the generation of individualized therapeutic applications in cognitive rehabilitation
Cognitive impairments are a major factor of loss of autonomy and dependence. They constitute a major problem of public health whose care is difficult and often beyond the expected efficacy. Rehabilita
An integrative analysis of nematode germline plasticity and evolution in different environments: from development to ecology
Understanding how developmental systems respond to environmental variation is of central significance in developmental and evolutionary biology. While both genetic and environmental factors contribute
Aortic stent-graft placement by augmented angio-navigation
The abdominal aortic aneurysm (AAA) is the most common aortic aneurysm. The endovascular treatment of AAA (EVAR - EndoVascular Aneurism Repair) has become an alternative therapy to conventional open s
Application of PICh for the characterization of the RNA Polymerase III transcription regulome
To exhaustively characterize RNA polymerase III regulators, one of the major process involved in the control of cell growth, we would like to set up a technique that will allow to purify 5S ribosomal DNA with its associated proteins.
