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Role of Neuronal signaling pathways in promoting intestinal smooth muscle maturation – NeuroPIMM
Gastrointestinal (GI) motility, i.e. the coordinated muscular contraction of the gut, is essential to the health and well-being of individuals of all ages. These movements originate from layers of smo
Innovative syntHEsis and Protection against Aging for Improved Skutterudite-based Thermoelectric generatOrS – I-Hephaistos
Thermoelectric generators convert heat into electricity and thus could help to harvest waste heat released from many industrial processes or empower remote sensors and actuators in extreme environment
From small to macrolactams: an enzymatic approach – SMALA
Biocatalysis is now a mature technology within the chemical industry landscape. Indeed many examples exist in which enzymatic steps have been implemented in industrial-scale synthesis, and complete en
Black-blood Magnetic Resonance Imaging and Automated AI-based Segmentation for Highly Detailed Characterization of Myocardial Scar – HEARTFACT
Cardiovascular diseases cause more than a third of all deaths in Europe. Late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) plays a central role in the management of patients with struct
Lipocalin-2 as a novel therapeutic target for retinopathy of prematurity – EliotROP
Retinopathy of prematurity (ROP; ORPHA:90050) remains the major ocular disorder of the neonate and the dominant cause of severe visual impairment in childhood in Europe and North America, but also in
Non-invasive gene therapy for Parkinson disease: Improve delivery of AAV vectors by single Intravenous delivery combined with Focused UltraSound (FUS). – FAB
Recent results demonstrated that gene therapy is an efficient strategy to treat rare or complex diseases of the central nervous system (CNS). Delivering therapeutic genes to the CNS mostly relies on A
TAGLN3 as a new regulator of neuroinflammation: from a biomarker to a biotarget in Alzheimer’s disease – TRANS3
Alzheimer's disease (AD) is a neurodegenerative disease remaining incurable yet. AD is a progressive disease with a silent phase for many years before the first symptoms of dementia. Identifying an ea
Carborane based vitamin D analogs for the treatment of rare disorder induced by hypervitaminosis D – CarBAV
The bioactive vitamin D (1,25D3) is a key regulator of calcium homeostasis. High circulating levels of vitamin D (calcitriosis) lead to hypercalcemia, and are a hallmark of several rare refractory ped
Combining molecular and functional genetics to decipher pathophysiological mechanisms in oculocutaneous albinism. – OCAGEN
Albinism is a rare disease associating generalized hypopigmentation and severe visual deficits in patients. Currently, the link between altered pigmentation and the retinal development anomalies that
Pathways and moleculaR analysEs to Derive multi-omIC signatures predictive to response to Treatment in JIA – PREDICT-JIA
Juvenile Idiopathic Arthritis (JIA) is an heterogeneous group of inflammatory arthritis, that cripples pediatric patients, with very little information available on the potential genetic contribution,