Search
The primary CILia, a new biomarker and actor in COLonic carcinogenesis? – CILCOL
Treatment options for ulcerative colitis improved significantly in the last years, but many patients are either non-responsive or become resistant during drug regimen underpinning the urgent need to d
Regulation of adrenal homeostasis by macrophages – ADREMAC
The adrenal cortex is a major regulator of body homeostasis through secretion of glucocorticoids in zona fasciculata (zF) and aldosterone in zona glomerulosa (zG). Alterations of the endocrine activit
Role of the POMC-ventral striatal neurocircuit in the development of diet-induced obesity – StriaPOM
Background: Due to the obesity epidemic, it is urgent to study diet-induced functional changes of neuronal circuits integrating the diverse components of feeding behavior (food hedonic and incentive s
Linking nuclear pores to chromatin organization and senescence – NPCOS
In most somatic cells, the heterochromatin accumulates at the nuclear periphery and around the nucleoli. How this global chromatin organization is established and maintained and how it participates in
NATURAL GENETIC VARIATION IN DROSOPHILA: AN ENTRYWAY TO INVESTIGATE THE DEVELOPMENT AND BEHAVIORAL FUNCTIONS OF THE VISUAL SYSTEM – WILD_EYES
Natural genetic variation affecting the nervous system is a major influence that shapes us as individuals. However, how small changes in our genomes cause dramatic changes in sensory perception and be
Exploring chromatin functions in yeast spores – EpiSpores
SCIENTIFIC CONTEXT. Unicellular organisms need to adapt to rapid and unanticipated changes in their environment. Spores ensure their survival by encapsulating the genome in a protective configuration
Enteroendocrine cells: differentiation and function – EEC
Enteroendocrine cells (EECs) are rare cells found along the intestinal mucosa and represent the largest endocrine system in the human body. EECs sense nutrients and dietary metabolites generated by th
Role of Neuronal signaling pathways in promoting intestinal smooth muscle maturation – NeuroPIMM
Gastrointestinal (GI) motility, i.e. the coordinated muscular contraction of the gut, is essential to the health and well-being of individuals of all ages. These movements originate from layers of smo
Innovative syntHEsis and Protection against Aging for Improved Skutterudite-based Thermoelectric generatOrS – I-Hephaistos
Thermoelectric generators convert heat into electricity and thus could help to harvest waste heat released from many industrial processes or empower remote sensors and actuators in extreme environment
From small to macrolactams: an enzymatic approach – SMALA
Biocatalysis is now a mature technology within the chemical industry landscape. Indeed many examples exist in which enzymatic steps have been implemented in industrial-scale synthesis, and complete en