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Phosphate capture enhancement in peritoneal dialysis process using designed recyclable iron oxide nanostructures – PHODIA
In patients suffering of chronic kidney disease (CKD), phosphates accumulation in blood is very dangerous and dialysis is the only way to remove them from blood, for those waiting for transplantation.
Exploiting autophagy-lysosomal dysfunction of immune cells as therapeutic target in periodontal diseases – TopGum
Periodontal diseases are inflammatory diseases of infectious origin. They are characterized by the destruction of tooth-supporting tissues and lead to tooth loss. The prevalence of periodontitis is hi
Endothelial therapy for ischemic stroke. – ETHERISCH
Ischemic stroke is a major cause of death and morbidity worldwide and therefore an important public health issue. Current treatment, limited to removal of the large vessel occlusion at origin of ische
Developing a SHERLOCK platform for multipurpose detection of trypanosomatid Parasites. – SherPa
Neglected tropical diseases caused by vector-born trypanosomatids - African trypanosomiases, Chagas disease and leishmaniases - affect both humans and animals, and disproportionately levy an economic
Innovative Neuroprotective Strategy Based on a New Class of Purine Derivatives for Neonatal Ischemic Encephalopathy – INSPIE
Hypoxia-ischemia (HI) is one of the leading causes of neurodevelopmental morbidities in infants. There are no pharmacological treatments. HI brain injury is characterized by inflammatory response alon
INFLAMMATION AND BLOOD BRAIN BARRIER INTEGRITY AS BIOMARKERS OF SUICIDAL BEHAVIOR. – IBBBIS
The prevention of suicidal behaviors (SB) is a major public health priority worldwide, especially since the phenomenon is feared to worsen in the context of the COVID 19 pandemic. The identification o
Targeting cellular MEchanisms of altered regeneration for ALcoholic hepatitis precision medicine. – MEdicAL
Alcoholic hepatitis (AH) is the most severe form of alcohol-associated liver disease (ALD). The pathogenesis of this life-threatening disease is complex and poorly understood due to the lack of animal
Lithospheric structure and fluid circulation in subduction system: impact on slip mode – FLUID2SLIP
Fluids, lithology and structure are known to play a major role in shallow fault slip modes but there is a major issue: Does one of them take precedence over the other two or are they linked? Are reall
Planet differentiation: an integrated Experimental and numerical Modeling of Germanium isotopic fractionation – PlanetGEM
How have planets in our Solar System formed and evolved to their present state? In the turbulent environment of the early Solar System, complex and successive stages of accretion-collision between ast
Mechanistic characterization of in vitro reconstituted bacterial cell division subcomplexes – MecaDiv
Bacterial cell division is a temporally and spatially regulated process coordinated by a multi-protein complex called the divisome. The assembly of the divisome is initiated and organized by a highly