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Mitochondrial and protease dysfunction in progeroid Cockayne syndrome cells and during age-associated processes
Understanding the molecular defects responsible for premature ageing diseases like Cockayne syndrome (CS), is critical to develop treatments, which are dramatically missing to date, and also elucidate physiological ageing. We identified an altered pathway that involves mitochondrial an metabolic dysfunction in cells from CS patients, and rescued these defects in these cells, by scavenging oxidative/nitrosative molecules, paving the path to therapeutic approaches for CS.
Operator Algebras and Group Dynamics
Operator algebras and group dynamics
Intégration et Développement des IdEx et des ISITE (IDéES) - Appel à projets – 2019
Appel à projets ouvert aux établissements porteurs d’une IdEx ou d’une ISITE
Structuration de la Formation par la Recherche dans les Initiatives d’excellence (SFRI) - Appel à projets - 2019
Appel à projets ouvert aux établissements porteurs d’une IdEx ou d’une ISITE
