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REsolving Systems Epigenomes of T-cells from Autoimmune and Inflammatory Disease patients
The recent surge in asthma (A) and Type 1 diabetes (T1D) incidence is often attributed to changes in environmental exposures, notably early infections. GWAS has revealed tens of loci where associated
Comprehensive Study of Small Noncoding RNA in Depression
Major depressive disorder (MDD) affects between 6.4-10.1% of the population and despite its prevalence and considerable burden, our understanding of the pathophysiology remains rudimentary. Several mo
Integrative Epigenomics of Obesity and Metabolic Complications – The Obesity Epigenomics Trilateral Project
Background: Obesity is a leading cause of death worldwide. Although the disease significantly increases the likelihood of type 2 diabetes (T2D) it remains unclear why not all obese patients develop T2