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An integrated multi-omics signature of kidney fibrosis for CKD precision medicine – KidneySign
Affecting around 10% of the population, chronic kidney disease (CKD) is a concerning disease of European societies, which ultimate stage (end-stage kidney disease (ESKD)) is irreversible and fatal if
Dihydroflavonol 4-Reductase (DFR) substrate specificity - Completing the puzzle. – DFR-SPEC
Dihydroflavonol 4-reductase (DFR) substrate specificity – Completing the puzzle Wider research context Dihydroflavonol 4-reductase (DFR) is a key enzyme in the biosynthesis of anthocyanins and cat
Urine biomarkers for bladder cancer initial detection and surveillance: a multicentric study to assess the diagnostic accuracy of a comprehensive tool. – UBIOBCA
Bladder cancer (BC) ranks as the tenth most prevalent cancer in the world (IARC, WHO), with a steady rise in its incidence and prevalence, and is accompanied by a high morbidity and mortality. Absence
Climate Hazards and Migration in Madagascar: Towards an Integrated Monitoring and Modeling for Mitigation and Adaptation – CHAIN
The increasing frequency and severity of sudden and slow-onset climate-related hazards are bearing visible effects on natural and human systems in low- and middle-income countries (LMICs). The consequ
LPCBioMab, Antibody-Functionalized Lipoprotein Complexes (LPC) including ApoA1 and a macrophage-repolarizing drug for the targeted therapy of atherosclerosis – LCPBioMab
The LPCBioMab project wants to develop a targeted therapy of atherosclerosis associated with a companion diagnostic tool. We aim to engineer biomimetic, biocompatible ApoA1-based lipoprotein complexes
Characterization of a new MisMatch Repair pathway – MMRDNABREAKS
Our multidisciplinary project will provide molecular insight into the novel mismatch repair (MMR) pathway dependent on the endonuclease NucS found in many archaea and actinobacteria. Inactivation of t
Hyperpycnal sediment-laden river plumes in lakes: flow-sediment-bathymetry interactions – HARP
Wider research context The focus is on the near-field flow dynamics and the flow-sediment-bathymetry interactions of hyperpycnal plumes, i.e., plumes induced by sediment-laden river inflows with a de
ORGAnic-MIneral systems evolution simulating aqueous alteration in Solar System bodies – ORGAMISS
While organic matter is a pivotal component of all Life on Earth, many unknowns surround its origin and evolution throughout the Solar System. Observation and identification of organic matter are majo
Theory and practice of differential elimination – OCCAM
Given a system of differential equations, the aim of differential elimination is to compute implied relations that only involve a set of variables of special interest. It generalizes the classical Gau
