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Effect of Titanium dioxide dietary particles on host-gut microbiota interactions: role of aryl hydrocarbon receptor and impact on the development of metabolic disorders and colon cancer. – TitADiet
Particles of TiO2 are used as colorant (additive E171) in several processed food. The aim of TitADiet is to explore the consequences of chronic oral exposure to E171 in the occurrence and/or the aggravation of metabolic disorders and intestinal tumor lesions. A link with intestinal dysbiosis and its consequences on the intestine, immunity and metabolism will be evaluated.