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The future for regenerative medecine: transdifferentiation by naturally secreted inducers of cell identity
A major goal of regenerative medicine is to produce cells that would participate to the regeneration or repair of damaged tissues and thus restore the altered function in disease, trauma or aging. Man
Ultrafast Acoustoelectric Imaging of the Heart In Vivo
The heart is driven by an electrical activation that propagates in cells and triggers their concerted contraction, which results in efficient pumping of the blood. The electrical activation sequence c
The use of pi interactions in the development of ultra-stable hydrophobic heterogeneous catalysts
Heterogeneous catalytic processes not only control the transformation of oil into petrol and petrochemicals, but also the mass production of commodity and fine chemicals, as well as most of the new bi
Host cell targets of bacterial infections: combining systems biology and mechanistic approaches
Identification and characterization of host targets of bacterial infections for the developement of new anti-infective treatments
Multiscale Modeling of bioMolecular Machines
We aim at developing advanced simulation schemes for investigating complex biomolecular systems whose functioning involves transient protein-protein interactions and large-scale conformational flexibility. To this end, we want to integrate experimental/bioinformatic information with molecular simulations at various scales. Method development will be coupled with the study of intriguing biomolecular systems in collaboration with experimental partner.
ORIGIN AND EVOLUTION OF THE VERTEBRATE EPITHELIAL APPENDAGES: AN INTERDISCIPLINARY PERSPECTIVE
The ambition of evolutionary developmental biology (evo-devo) is ultimately to devise a mechanistic theory that would link the processes of individual development with phenotypic change during evoluti
Virtual Reality for Training Doctors to Break Bad News
This project aims at exploring the question of multimodal natural language interaction, its theoretical basis and its experimentation into a virtual reality environment thanks to the development of an
Pericyte-mediated vessel maturation in cancer therapies
Judicious application of anti-angiogenesis agents can correct vessel abnormalities to improve response to conventional cancer therapies. However, the concept of vascular normalization is relatively yo
Organic Photochromic Dyes for Photovoltaic Applications: Towards New Solar Cells with Self-Adjustable Optical Transmission
This project aims at designing and synthesizing photochromic dyes suitable for the sensitization of wide band gap inorganic semiconductors and ultimately it targets the development of a new class of m
Inhibition of platelet Protease Nexin-1 as a promising anti-bleeding strategy in haemophilia
Haemophilia A and B are inherited X-linked coagulopathies characterized by a lack of coagulation Factor VIII (FVIII) and factor IX (FIX) respectively. Haemophilia A affects about 1 in 5 000 and Haemop
