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A new biphasic microgel as lipoxin delivery system for tissue engineering – BILIPOX
We hypothesize that exogenous provision of LXA4 could dampen excessive inflammation in pulpitis and peridontitis. The specific goal of this project is to evaluate the potential benefits of a new Biphasic Microgel (BPMG) as lipoxin A4 (LXA4) delivery system. This functionalized BPMG aims both to modulate inflammation and to promote tissue repair or regeneration in pulpitis and periodontitis
A new medical device to reduce the urinary lithiasis recurrence – URITRACK
The recurrence of the kidney stones (or urinary lithiasis) increases in all industrialized countries implying an increasing cost for healthcare systems. In this project, we propose to reduce it by dev
A new tool for the assessment of Speech Sound Disorders in French-speaking children – EULALIES
Children with Speech Sound Disorders (SSD) ‘‘can have any combination of difficulties with perception, articulation/ motor production, and/or phonological representation of speech segments (consonants
A rare disease to decode the functional link between DNA methylation and maintenance of centromere integrity – MEliCENDre
In all living organisms, maintaining genome integrity and ensuring the proper transmission of genetic information at each cell division are key to healthy development and survival. In mammals, both DN
A risky market? The emergence of predictive maintenance of military systems in France – PREDICT-OP
Predict Op studies the emergence of digital data markets in the military domain from a dual perspective of economic sociology and organizational sociology. This concerns both the predictive maintenance of equipment, the «soldier of the future« and the construction of an infrastructure capable of supporting the transmission of massive data (data center, etc.).
A study on Dishonesty: from Emotions and Cognition to InStItutions and OrganizatioNs – DECISION
Dishonesty is a pervasive phenomenon of our society with extremely detrimental consequences for society, negatively impacting<br />growth, democracy and living conditions. It increases transaction costs, reduces trust, impedes the functioning of the political system, and undermines security. Understanding the factors that influence the decision to act dishonestly is of fundamental importance in order to understand many economic behaviors.
A system view of lung fibrogenesis using spatial transcriptomics – Lustra
Pulmonary fibrosis is a deadly disease for which the only therapeutic option is lung transplantation. Pulmonary fibrosis is a chronic and progressive disease characterized by the destruction of the al
A therapeutic target for ischemic related injuries, application to organ transplantation – KIRI
This project aims to design a new generation of pharmacological inhibitors capable of countering the consequences of an ischemic episode. They target a protein (serRS) that we have recently identified and implicated in the resistance of organs to ischemia. The clinical application is kidney transplantation.
A therapeutic wound dressing technology to prevent early osteoarthritis development following traumatic knee injuries – ARTiTHERA
Trauma is one of the most important risk factors for osteoarthritis. Repairing osteochondral lesions soon after the trauma could prevent or delay the onset of osteoarthritis. Unfortunately, there is a