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TREK-1 channel is Activated By Oxidized Omega-3 metabolites – TA-BOOm
TREK-1 is a potassium channel that plays a pivotal role in many physiological functions through its effect on membrane potential. The modulation of its activity can correct pathologies such as epilepsy, pain and cardiac ischemia. The discovery of new molecules derived from the oxidation of polyunsaturated fatty acids with natural origin capable of activating this channel opens up new perspectives to cure these diseases.
PhotobiofilmExplorer – PhotobiofilmExplorer
It is crucial to identify new drugs to deal with pathogens that are resistant to current antibiotics. Most of the microalgae species cultivated in biofilms by the start-up Inalve are capable of forming biofilms that are highly resistant to biological contamination thanks to the synthesis of allelopathic compounds. <br />The objective of the project is to characterise and produce these new bio-compounds that can be used for human and animal health.
Eco-extraction of bioactive compounds from red fruit pomaces and their impact on intestinal homeostasis – EcoActiFruit
Byproducts valuation and bioactive compound extraction
WAter in TEM – WATEM
Study of the interaction Water vapor / aerosols at the sub-micrometer scale: follow in real time the water uptake and the dissolution of nanometric particles and their evolution as a function of relative humidity in an Environmental Transmission Electron Microscope (ETEM)
Tax reforms and tax revolts in democracies – TAXREV
Questions linked to the design and implementation of redistributive tax policies have occupied a growing position on the public agenda over recent years. Moreover, the fiscal pressures brought upon by the current coronavirus crisis will ensure that these issues maintain considerable political significance for years to come.
Labour Brokers in Asian Migrations in French Colonial Empire of Asia and Pacific, from early 19th to the mid-20th century – COOLIEBROKERS
Critical study of the «brokers« in the organization of the Labour migrations in the Asia and Pacific French colonial empire, from the beginning of the 19th to the middle of the 20th century
Role of potassium transport in rice in securing high crop yields – RiceKTrans
Crops that use nutrients more efficiently than currently available varieties can help achieve more sustainable agriculture. Potassium (K+) is the most important cationic nutrient. However, little is known about the transport proteins that mediate K+ fluxes in cereals. In the proposed project, we will study K+ efflux channels and K+ transporters that enable K+ nutrition of aerial parts in rice.
Simulations and Observations of Uranus and Neptune atmospheric Dynamics – SOUND
Simulations and observations of Uranus' and Neptune's atmospheres to understand their atmospheric dynamics and climate.
Orchestration in time and space of southeast Tibetan faults, views from geology and geodesy – Tibetan-Orchestra
The eastern edge of the Tibetan Plateau is a key location to study the interplay between strike-slip motions and thickening through time and understand the regional orchestration between lateral propagation and crustal thickening of the plateau .
Probing the 3D Alpine lithosphere by Full Waveform Inversion of the AlpArray teleseismic data – LiSAlps
The Alpine chain has historically been one of the most epitomic natural laboratories to simultaneously study various deep and shallow geological processes controlling orogenesis due to their outstanding outcrop conditions. In this context, the objective of LisAlps project is to develop next generation models of the crust and uppe mantle of the Alps by applying leading-edge seismic imaging techniques such as Full Waveform Inversion (FWI) to the dense AlpArray teleseismic data.