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Towards the prevention of vascular dysfunctions and the targeted delivery of drugs through the endothelia
We have discovered a new mode of opening of transendothelial macroaperture (TEM) tunnels, which is driven by the relaxation of the actomyosin cytoskeleton leading to a cellular dewetting phenomenon. We identified key biochemical and physical parameters withstanding cycles of TEM opening and closure. We aim at identifying molecular players that control extension/resealing of the TEMs. The cellular dewetting hypothesis implies a membrane curvature-sensing mechanism that we propose herein to unveil
SUStainable production of HIgh quality aquaculture FISH using innovative tools and production strategies and integrating controlled slaughter and novel processing methods and cold chain management
Aquaculture production has a lower carbon footprint/kg meat compared to terrestrial production systems, there are clear health benefits of consuming fish and aquaculture removes dependence on wild fis
Integrated Multitrophic Aquaculture for EFFiciency and Environmental ConservaTion
Aquaculture is facing a double challenge: producing more to sustain a growing demand for aquatic products and preserving the environment. Integrated Multi Trophic Aquaculture (IMTA) is one of the most
Probing Alpine geodynamics with state-of-the-art seismic arrays and tomography
While most concepts that underlie current studies of mountain belts and convergence dynamics were born in the Alps, this belt has not been given the attention it deserves using recent geophysical techniques. The ambition of the European AlpArray collaborative project is to re-evaluate the deep structures and processes that occur beneath the Alps by exploiting cutting-edge developments in geophysical imaging.
Very High Field DNP / MAS NMR
The optimization of the structural and magnetic properties of the polarizing agents has significantly contributed to the increase of the signal enhancement at 9 T and to the success of the technique. However, ssNMR/DNP still faces important disadvantages, such as non-optimal signal enhancement and a poor spectral resolution due to the low temperature of the experiments. Moreover, at high field (18 T), the gain in sensitivity is dramatically reduced in regards with experiments performed at 9T.
Regulation, Diagnostics and Therapy focusing on the mineralocorticoid receptor involved in cardiac remodelling
The incidence of heart failure (HF) is increasing because of ageing of the population, while the prevalence at least of systolic HF is also increasing because of improved survival, as a result of life
Micro-RNAs of neutrophils in renal ANCA-associated vasculitis
Activation of neutrophils by ANCA (“Anti-Neutrophil Cytoplasm Antibodies”) and subsequent microvascular endothelial cell damage is the main feature of ANCA-associated vasculitis (AAV), a severe autoim
Towards Ubiquitous GRAphene based RF COmmunications ? demonstrating and understanding graphene based plasmonic THz antenna potential and limitations
Nanotechnology is increasingly providing a plethora of new tools to design and manufacture miniaturized devices such as ubiquitous sensors, wearable electronics or pervasive computing systems. Such de
Induced Spin Textures in van der Waals Heterostructures
After the discovery of graphene it was soon realized, that graphene is the perfect candidate for spintronics, due to its high mobility, low spin-orbit coupling and small or absent hyperfine fields. By
2D functional MX2-graphenes
The 948 has produced many exciting and valuable results so far. One of the main obstacles for real uptake in the industry however is the lack of scalable processes for making large area, high quality