Mitochondria are cellular organelles responsible for the production of ATP, the chemical fuel of the cell. Several metabolic cycles occur within this compartment. The function of this organelle necessitates the exchange of several types of metabolites and small molecules between the mitochondrial matrix and the cytoplasm. The project aims at understanding the transport mechanisms at a molecular level, more specifically the role of essential membrane proteins, the mitochondrial carriers.
Towards coherent radiation produced by particule beam accelerators injected with external lasers – DYNACO
In accelerator-based systems, a strategy for producing coherent radiation consists of injecting external laser pulses on a relativistic electron bunch. The resulting shaping of the electrons (bunc
Application of PICh for the characterization of the RNA Polymerase III transcription regulome – PIChClassIII
To exhaustively characterize RNA polymerase III regulators, one of the major process involved in the control of cell growth, we would like to set up a technique that will allow to purify 5S ribosomal DNA with its associated proteins.
Angiogenesis inhibition has led to impressive results in clinical trials in a variety of human cancers. Most anti-angiogenesis strategies are based on the inhibition of VEGF. Another field where anti-
Tubular structures are used in most industrial sectors. Present in numerous industrial processes for the transport of reagents, their injection or cooling devices, they are found especially in the agr
Implementability and Robustness of Timed Systems
MOUVE is is a research consortium integrated by INRA, CIRAD and Cemagref researchers in partnership with universities and research centres in Developing Countries. The purpose of the project is to pr
Pluripotent stem cells can differentiate in all cell types of an organism. During this process they progressively develop a narrower potential that results in commitment to specific cell fate with specific gene expression profile and functional property. Understanding how this process is regulated is of main importance both on fundamental and medical aspects. This is the objective of our project that focuses on a newly characterized actor believed to play a key role in cell fate determination.
-Genetic Diversity and Phenotypic Monotony in non-atherothrombotic arterial pathologies - 2 – GDPM-2
The etiologic diversity of TAAD, our ability to have access to human clinical cohorts and DNA collections, to diseased as well as normal human aortic tissues, and to obtain primary cultures of aortic
3D is becoming a real challenge in the futur of digital entertainment. The 3D digital cinema market is growing fast, but 3D TV, and 3D video games are going to be two other major market in a near futu