Sustaining a growing population while preserving nature is challenging, especially in an increasingly unpredictable climate. In this context, high production levels of fine wine will require innovations. Such breakthroughs are likely to arise from experimenting with the grape must’s microbial community that determine many wine characteristics. We propose to study the evolutionary genetics of the main wine yeast, S. cerevisiae, in its microbial community.
Mountains to Climb in the Chemistry of Highly Complex Indole Alkaloids: Methodology for Total Synthesis – Mount-Indole
Bipleiophylline is one of the most complex monoterpene indole alkaloids.
Mononuclear phagocytes (MP) comprise a family of cells that include monocyte (Mo), resident macrophages (rMf) such as microglial cells (MC), and monocyte-derived inflammatory macrophages (iMf) that ar
Non-alcoholic fatty liver disease, the hepatic hallmark of the metabolic syndrome, and alcoholic liver disease are leading causes of chronic liver injury that share common pathophysiological features,
Arctic is faced with global warming. The melting of the arctic pack ice and ice cap is dramatically changing the conditions of life for animals and humans. New territories are free for economical acti
Molecularly-directed hybrid nanobuilding block self-assembly towards original 2D and 3D mesoscale architectures for catalysis – MODULE-CAT
This project describes a modular approach to novel 2D and 3D functional structures based on metal-substituted silesquioxanes and lamellar self-assembled silica structures. For 3D structures, we aim at
One of the main current challenges in nanosciences is the exploitation of single molecular machines for mechanical applications in the real world. In the proposed project, molecular design, chemical s
Molecular design of biocatalytic 3D nanocarbon architectures for longlasting glucose fuel cells. – Mocca-Cell
This project aims at developing high power enzymatic glucose biofuel cells with enhanced operational lifetime. It includes the design of an electron shuttle for glucose oxidation with tailored redox