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undestanding pigmentary abnormalities in Xeroderma pigmentosum
One of the first clinical manifestations in xeroderma pigmentosum (XP) patients is alteration in the skin pigmentary phenotype, which has been neglected from a mechanistic standpoint until now due to
understanding and MOdeling NOx formation in Turbulent HYdrogen flames
Hydrogen combustion is a promising energy source to reach the carbon neutrality in 2050 in many applications. This objective raises great scientific challenges in terms of combustion, as the chemical
underground STOrage of reneWable ENergies in low permeability Geomaterials
Underground STOrage of reneWable ENergies in low permeability materials
ultraSHOrt tunable deep-and vacuum-UV generation for TIME-resolved molecular dynamics
The ShoTime project aims at producing bright and reliable sources of tunable ultrashort Vacuum- and Deep-UV pulses (120-350 nm, sub-10 fs) at 166 kHz repetition rate, and at using them in combination
ultra-wide Bandgaps for futuRE high power electronic ApPlications
The aim of this project is to explore and to develop radically new material systems based on AlN ultra-wide bandgaps for future power devices providing higher robustness and superior temperature operation towards the ultimate all-binary AlN/GaN/AlN heterostructure. The AlN material will enable high efficiency operation beyond 1200 V as well as higher power performances in the millimeter-wave range, which is not currently reachable by GaN devices.
ultra-violet light emitting diode based on tunnel effect
Light Emitting Diodes (LED) based on nitrides are very efficient and worldwide used for solid state lighting. In the ultraviolet, however, their wall plug efficiency remains severely limited by the p
ultra-High-spEed high-Resolution force Microscopy and spEctroscopy of biological Systems
HERMES aims to develop a new generation of vibrating probes for atomic force microscopy using optomechanical technology. Endowed with a frequency reaching the GHz, a thousand times higher than that of the usual probes, and capable of resolving Brownian motion at room temperature, these probes open the way to an unprecedented experimental window in terms of speed and temporal resolution for observing and characterizing molecular biology processes.
ultra-High-spEed high-Resolution force Microscopy and spEctroscopy of biological Systems
HERMES wants to take high-speed atomic force spectroscopy and microscopy (AFM) to the next level, opening a new experimental window in molecular biophysics experiments. We will develop nanosecond atom
uORF-mediated post-transcriptional control of stem cell niche activity in plants
Target of Rapamycin (TOR) functions as a central hub to link a wide range of external stimuli to protein production. In plants, protein production is limited by upstream open reading frames (uORFs) located within the 5’UTRs of about 30% of eukaryotic mRNAs. The mechanism of uORF-mediated suppression of translation and reinitiation factors that mediate uORF inhibitory potential are not yet clear.
