Molecular characterisation of the assembly and functioning of a membrane complex: the NADPH-oxidase – PROTOTYPE NOX
The NADPH oxidase is a part of numerous membrane proteins of which the three-dimensional structure was not able yet to be determined in spite of numerous efforts in the development of the production and purification techniques. However the knowledge of its structure and its functioning stays a major stake due to its pharmacological importance. That is why since a few years our efforts aim at the elaboration of a system of effective production of this enzyme.
Diabetes mellitus is a serious, debilitating, currently incurable, costly disease that afflicts some 220 million persons worldwide. Currently not only the incidence of type 2 but also of type 1 diabetes progresses considerably. These patients are either treated lifelong with insulin injections or in some cases receive islet transplantations.
novel dilute nitride III-V Compound sEmiconductoR for 1550nm Ultra-Fast PhotoconductIve SwitchE – CERISE
Dilute nitride materials are the material system that enables photonic devices working at the optical telecommunication wavelengths of 1300 and 1550nm on a low cost GaAs platform instead of the incumb
This project intitled «Nanofabrication and magnetic active cell patterning for vascular engineering», acronyme NMVASC, is submitted to the ASTAR/ANR Joint Call for Proposals in Nanotechnology area.
ABSTRACT Retinal degeneration has been associated with iron accumulation in age related macular degeneration (AMD) and in several rodent models which had one or several iron regulating proteins i
De nombreux diagnostics reposent sur des biopsies, dont la mise en œuvre crée une lésion, et donc un risque pour le patient. D’autres dépendent d’analyses effectuées a postériori en laboratoire, ce qui retarde d’autant le résultat et la mise en œuvre du traitement associé. FIR-MED propose de développer un outil alternatif, basé sur un capteur optique infra rouge. <br /> <br />
The objective of RUBI-CLOCK is to bring the concept of a compact atomic clock based on cold atoms to a technology readiness level that will allow a transfer towards industry. Compared to the compact c
Viscoelastic characterization of industrial fluids using acoustical rheology. Application to cosmetics and concretes. – RHEACTIF
The material viscoelastic properties assessment covers a wide range of industrial and research problematics, particularly in cosmetics/pharmaceutics, cements/concretes, foods, polymers and petroleum p
Graphene is the only example of "bi-dimensionnal crystal" : it is made of a layer of carbon from which the stacking constitutes the graphite in the tri-dimensional space. It has been isolated for the
Targeting of the Tn antigen by a specific chimeric monoclonal antibody in ovarian cancer immunotherapy – ANTITN
Therapeutic monoclonal antibodies (mAb) specific for tumor-cell surface antigens are efficient at eradicating patients’ cancers. These enthousiastic results encourage us to develop new tumor-specific