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Sustainable Tomato Production: plant defense enhancement, development of new biopesticides and optimization of environmental, water and chemical inputs
Tomato has a very high social and economical relevance in Europe and the whole Mediterranean area. The manifestation of new tomato diseases and invasive pest is promoted by climate change and globaliz
Mediterranean Extra Virgin Olive Oil Omics: profiling and fingerprinting
Olive oil is one of the oldest vegetable oils, and is the major constituent of the Mediterranean diet. Its consumption has also spread remarkably outside the Mediterranean Basin. It is considered as a
Emergent viruses and virus vectors in Mediterranean Basin crops
Emerging plant viral diseases represent a significant burden to plant health, and their highest impact in Mediterranean agriculture is on vegetables grown under intensive horticultural practices. Inte
Globally Observed Teleconnections and their role and representation in Hierarchies of Atmospheric Models
GOTHAM represents an ambitious research programme to gain robust, relevant and transferable knowledge of past and present day patterns and trends of regional climate extremes and variability of vulne
PAlaeo-Constraints on Monsoon Evolution and Dynamics
This project uses annually-resolved palaeoenvironmental records of climate variability over the past 6000 years from corals, molluscs, speleothems and tree rings, together with global climate-model simulations and high-resolution simulations of the Indian, Africa and South American monsoons, to provide a better understanding of monsoon dynamics and interannual to multidecadal variability (IM).
Climate Services Through Knowledge Co-Production: A Euro-South American Initiative For Strengthening Societal Adaptation Response to Extreme Events
An inter- and trans-disciplinary framework based on a European-South American research cooperation is proposed to underpin climate services inSouth America. Climate variability patterns linking the S
Improving PREdictability of circumboREAL forest fire activity and its ecological and socio-economic impacts through multi-proxy data comparisons
The ability to predict forest fire activity at monthly, seasonal, and above-annual time scales is critical to mitigate its impacts, including fire-driven dynamics of ecosystem and socio-economic serv
Novel drugs and drug combinations against bacterial growth, survival and persistence from high-throughput screening to mechanism of action
Control of bacterial infections is threatened by the rapid emergence of drug resistance, drug tolerance that mitigates antimicrobial efficacy, and the lack of new antibiotics in recent years. Combinat
Developing combinations of CO-ACTIVE antimicrobials and non-antimicrobials
The CO-ACTION project aims to develop and provide a framework for evaluating and validating the effectiveness of antibiotic- and non-antibiotic combinations (COMs) in the preclinical setting based on
Repurposing disused antibiotics with immune modulators as antimicrobial strategy for respiratory tract infections
Respiratory tract infection is the third cause of death worldwide. Although antibiotics are recognized as an effective therapy, treatment is often associated with failure due to resistance to antibiotics. The pathogenic bacteria: Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, and Streptococcus pneumoniae are the most relevant causes of pneumonia. Our proposal aims to develop non-traditional combination therapies to minimize treatment failure.
