Pollinators and pollination underpin ecosystem and human health but they face multiple threats from global change. Anthropogenic modification of landscape floral resources by land-use and alien specie
Viral dynamics at the individual and population levels: impact for antiviral treatment optimization – TheraCoV
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which originat-ed in Wuhan, China, has become pandemic and a major concern all over the world. By March 22, 2020, this vir
Viruses hijack the molecular machinery of host cells to complete their replication cycle, a process frequently associated with the production of double-stranded RNA (dsRNA). We aim to unravel the mole
The proposal "Viro-DUB" : "Viral deubiquitinases : new players in the control of plant virus infections" aims at the elucidation of novel molecular and cellular mechanisms underlying host/virus intera
Cellular homeostasis requires permanent cellular surveillance and response to internally and externally inflicted insults. Such insults include the DNA damage response (DDR) and the unfolded protein r
The objective of the Civyq project is to respond to the "Epidemic and social dynamics" research axis of the Action Liban 2021 project. It addresses several themes of this axis: the production of norms
Viral circulation and sharing in sympatric bat and rodent species living at a close interface with humans and risks of zoonotic spillover in southern Africa. – VICTORIA
The risk of EIDs for human societies is real: outbreaks of Ebola viruses or yet the newly emerged SARS-CoV-2 are the most well-known recent examples of EIDs which emerged locally with a subsequent lar
Light-activated proteins of the rhodopsin family, found in all three domains of life, have also been found to be encoded by giant viruses. Little is known on these virus-encoded rhodopsins. Their structure, oligomeric organization, and function are unknown. In spite of significant similarity, viral rhodopsins differ greatly from known rhodopsins. These proteins could involve novel biological mechanisms and sustain possible applications in optogenetics.
Cell intrinsic innate immunity is the first and crucial barrier that controls virus infection upon entry into a target cell. Recognition of viral infection very often involves detection of virus speci
Our project aims at defining this newly discovered aspect of the innate immune response triggered by cell-to-cell contacts between virally infected cells and cells specialized for the antiviral response. In particular, we determine the importance of the cell contacts, the carrier of the transmission, the viral and cellular determinants and the induction pathway.