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Axon Guidance and Regeneration of the central nervous system
Nervous system diseases represent more than 35% of Europe’s total illness burden. The impairment of central nervous system (CNS) often affects vital functions such as vision in the cases of glaucoma or motor function in the case of multiple sclerosis or spinal cord injuries. People suffering from CN
Manuscripta Bibliae Hebraicae. Hebrew Bible Manuscripts in Western Europe (England, France, Germany, Italy) in the 12th and 13th centuries: A Material, Cultural and Social Approach
Manuscripta Bibliae Hebraicae (ACHN MBH) Hebrew Bible Manuscripts in Western Europe (England, France, Germany, Italy) in the 12th and 13th centuries: A Material, Cultural and Social Approach This project examines the place of the Hebrew Bible in Christian Western Europe during the Middle Ages a
Ferroelectric Molecule-Based (Magnetic) Materials
The aim of the FEMMM project is to develop new ferroelectric molecule-based (magnetic) materials. Ferroelectric materials featuring electric bistability provides diverse entries into technical applications. During the last decade, molecular ferroelectric materials have received much interest largely
Biomechanics of intra-oral water flow generation in fish
The head of a fish is a remarkably mobile structure used for vital functions such as food capture and respiration. But how do fish efficiently generate the water flows that specifically meet the biomechanical requirements of these functions? Although the water flow inside the mouth cavity fulfils a
Between France and Italy: female mysticism and politics in the modern era
The reserarch sets out to analyse the relationship between politics and female mysticism, comparing France and Italy, with a major focus on North Italy and the State of Savoy, which was constantly influenced by French culture and spirituality, between the Baroque era and the first half of the Twen
Self-interacting and asymmetric dark matter
The cosmological formation of bound states by dark matter coupled to light force mediators. The effect of unstable bound states on the relic density of dark matter. The expected radiative signals from the formation of bound states inside haloes. Viability of self-interacting dark matter models. C
Functional ecology of parasitic protists in benthic ecosystems
Marine ecosystems play a central role in geochemical cycling and climate regulation. These environments harbour complex and cryptic communities, dominated in terms of abundance and biomass by planktonic microbes including bacteria, archaea, viruses, and eukaryotic organisms (such as protists and fun
Functional characterization of erythroferrone and therapeutic applications
The liver has emerged as the central regulator of iron homeostasis. It produces the hormone hepcidin, which controls body iron content and the distribution of iron to tissues. Hepcidin controls the major flows of iron into plasma: absorption of dietary iron in intestine, recycling of iron by macroph
The Factory of Antiquity in North Africa : Archealogies and Heritages in Algeria, Tunisia and Morocco (XIX-XXI)
In his Dictionnaire des idées reçues, Flaubert characterizes “Antiquity and all what is related to it” as “cliché, annoying”: the ambition of this project and of its summary is to proceed in such a way its readers will not subscribe to this definition! “The Making of Antiquity in the Maghreb: Arche
Contested Global Governance, Transformed Global Governors? International Organisations and “Weak” States
This project aims to explore the ongoing contestations of global governance interventions of international organisations (IOs) by ostensibly “weak” states and the impact of such contestations on IOs. It proposes to approach these issues in a theoretically, empirically and methodologically innovative
Coupling donor and quantum dot in silicon for applications in quantum information processing
Quantum physics, when applied to computing, is projected to lead to revolutionary enhancements in computational speed and power. However, to construct such a "quantum” computer, its building blocks, called qubits, have to be resistant to environmental disturbance; they need to hold the information
Fusion Of Modeling And Data Analysis To Study The Evolution Of Pathogens
Pathogens evolve rapidly to circumvent drug treatments and immune surveillance, which dramatically impacts public health. To develop effective treatments, we must interpret pathogen’s genetic sequence; however, our efforts are complicated by their high genetic diversity within and across infected in
Correlated fluid of light : hydrodynamical and thermodynamical aspects
Light has been since the beginning of the XXth century described as a gas of photon, with limited interactions. Since the recent development in semiconductor fabrication, this picture tends to be overcome, to welcome a new analogy connecting light to fluid. Nowadays the interaction between photons c
Assessing CHILdren Exposure to environmental chemicals using target and non-target strategies
Assessing human exposure to chemicals can be carried out by measuring chemicals or their biomarkers in human specimens. This approach allows an aggregate measure of exposure that provides a picture of the amount of chemicals absorbed into the body considering all routes of uptake and all sources. A
Carrier Multiplication in Perovskite nanostructures studied by Ultrafast Ultraviolet/visible fluorescence Spectroscopies
The aim of the CaMPUUS project is double. On the one hand, it is to develop a two-dimensionalspectroscopic technique in the UV/visible range. Only a few such setups exist in the world, and none in France. On the other hand, this new setup, combined with a femtosecond fluorescence technique existing
Long-run Relationships without Money
The application’s theme is mechanism design without transfers. This leaves two instruments to the designer: allocation of goods, and provision of information. It proposes to apply and develop tools in game theory and economic theory to understand how private information can be elicited and used to m
Physics of hydrogen and other light elements under extreme conditions.
In 1935 Wigner and Huntington speculated that metallization in compressed hydrogen should occur at around 25GPa. Present experiments have reached about 350GPa without finding the metallic phase yet. It is now predicted to occur at 400GPa at low temperature. This mismatch is emblematic of the unexpec
Small RNA-directed heterochromatin establishment
Heterochromatin is a closed and mostly transcriptionally repressed state of chromatin, which is critical for gene silencing, cell differentiation and genome maintenance. Although how heterochromatin is maintained through cell proliferations is well understood, how heterochromatin is formed in the fi
Assessing the relationships between marine protected areas and invasive species
The project is focused on the relationships between MPAs and alien/range-expanding fish species in the Mediterranean Sea, and aims to answer the following three questions: 1) Do MPAs influence the expansion of alien/range-expanding species and mitigate their effects on native assemblages? 2) Can
Interactions of Control, Partial Differential Equations and Numerics
This project aims at making a breakthrough contribution in the broad area of Control of Partial Differential Equations (PDE) and their numerical approximation methods by addressing some key issues that remain badly understood or unsolved and which appear systematically in all real-life applications.
Engineering multi-photon dissipation in superconducting circuits for quantum error correction
Technologies exploiting quantum properties such as entanglement and superposition, could revolutionize our computational abilities. In the last two decades, impressive theoretical and experimental progress have brought us closer than ever to building these technologies. However, some outstanding cha
Development of the immune system
Lymph nodes and lymphatic vasculature are an essential part of the adaptive immune system. Properly placed lymphatic vessels and lymph nodes are crucial for an adequate and fast immune response. It is therefore not surprising that both lymphatic vessels and lymph nodes are formed in a coordinated fa
Indigenous geographies: roots, developments and perspectives in the french-speaking universe
The INDIGEO project engages an epistemological reflection on the formation of indigenous geographies, defined as a field of research interested in the different territorial configurations arising from the spatial manifestations of Indigenous peoples and their identities. In France, despite the incre
Atomic-scale electron correlations using time-resolved scanning tunnelling microscopy
The dynamics of exotic systems such as oxides (high-temperature superconductors, manganites, irridates…) and heavy fermion materials contains important clues to the mechanism driving the often unanticipated and technologically very relevant properties. To gain access to the dynamics of electronic co
In vivo quantification and manipulation of mechanical forces across muscle attachment sites and sarcomeric proteins during muscle morphogenesis
The contractile unit of all muscles is the sarcomere. Sarcomeres are arrayed into chains called myofibrils, which span the entire muscle fiber. Both muscle fiber ends are attached via tendon cells to the skeleton. Thus, coordinated contraction of the sarcomeres results in a defined body movement. We