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Brain-Inspired PHOtonic PROCessor – BIPHOPROC_2
BiPhoProc aims to demonstrate a highly innovative self-consistent bio-inspired computer, which hardware architecture is based on a hybrid digital (FPGA) and optoelectronic systems. The computing efficiency will be moreover demonstrated on real-world complex technological tasks, in stead of usual sta
The use of pi interactions in the development of ultra-stable hydrophobic heterogeneous catalysts – PICATA
Heterogeneous catalytic processes not only control the transformation of oil into petrol and petrochemicals, but also the mass production of commodity and fine chemicals, as well as most of the new biomass-derived chemicals and energy vectors. Despite the variety of reactions and active phases invol
Organic Photochromic Dyes for Photovoltaic Applications: Towards New Solar Cells with Self-Adjustable Optical Transmission – ODYCE
This project aims at designing and synthesizing photochromic dyes suitable for the sensitization of wide band gap inorganic semiconductors and ultimately it targets the development of a new class of multifunctional photovoltaic devices. It addresses fundamental questions regarding the potential appl
Brain-Inspired PHOtonic PROCessor – BIPHOPROC
BiPhoProc aims to demonstrate a highly innovative self-consistent bio-inspired computer, which hardware architecture is based on a hybrid digital (FPGA) and optoelectronic systems. The computing efficiency will be moreover demonstrated on real-world complex technological tasks, in stead of usual sta
Can carbon nanotube scrutinize intimate tissue organizations? Uncovering early dys-organization of the brain extracellular space in Parkinson disease – nanoSPACE
Most types of cell communication in the brain require the transfer of molecules through the extracellular space (ECS). A correct transfer of molecules within the ECS is thus essential to convey both local and long-distance communication. Although ECS is often considered as a static space with foam o
Inhibition of platelet Protease Nexin-1 as a promising anti-bleeding strategy in haemophilia – ISPAHAN
Haemophilia A and B are inherited X-linked coagulopathies characterized by a lack of coagulation Factor VIII (FVIII) and factor IX (FIX) respectively. Haemophilia A affects about 1 in 5 000 and Haemophilia B about 1 in 35 000 male births. Haemophilia leads to impaired thrombin generation, weak and v
Ultrafast Acoustoelectric Imaging of the Heart In Vivo – ULTRAFASTACOUSTOELEC
The heart is driven by an electrical activation that propagates in cells and triggers their concerted contraction, which results in efficient pumping of the blood. The electrical activation sequence can be disrupted by disease, a condition referred to as conduction disorder, or arrhythmia. For examp
Neutron investigations to reveal anapoles: a route for a high-temperature superconductivity mechanism in copper oxides – NirvAna
The project NirvAna aims to evidence anapoles (or polar toroidic dipoles) in condensed matter physics and more particularly in high temperature copper oxide superconductors. A spontaneous circulating loop current state, belonging to the anapole class, has been proposed to be the driving force contro
Transgenic marine embryos as sentinels detecting CMR toxicity in the sea. – MarineEmbryoTox
The density of human habitation around the Mediterranean sea is the highest in the world making it an ideal site to monitor man-made pollution of a marine environment, which could also affect humans. Here we set out the case for choosing the ascidian as the ideal animal model to monitor pollution.
Self-Assembled Magnetic Materials with New Paradigms – SMARAGD
Our latest experimental results and calculations prove that the paramagnetism of gold nanoparticles is of orbital nature and results from the conduction electrons being driven into persistent currents by external magnetic fields. Moreover, when the nanoparticles are organized in a regular 3D lattice
Does regeneration reset the age clock? – reAGE
The dream of regenerative medicine – to regenerate functional organs as replacements for damaged or amputated parts of our body – has captured the public interest. In public imagination regeneration is sometimes also associated with rejuvenation, the reversal of ageing. We know that certain populati
Helical states and Majorana fermions in topological nanostructures – TOPONANO
The mathematical concept of topology applied to condensed matter has been very helpful to understand the transport properties of certain materials. This description was responsible for the discovery of new states of matter called topological insulators. These are insulating in the bulk of the materi
The future for regenerative medecine: transdifferentiation by naturally secreted inducers of cell identity – iTraNS
A major goal of regenerative medicine is to produce cells that would participate to the regeneration or repair of damaged tissues and thus restore the altered function in disease, trauma or aging. Many strategies are being pursued today to obtain therapeutic cells of clinical interest, either ex viv
Pericyte-mediated vessel maturation in cancer therapies – Ang_maturation_cancer
Judicious application of anti-angiogenesis agents can correct vessel abnormalities to improve response to conventional cancer therapies. However, the concept of vascular normalization is relatively young and strategies targeting Vascular Endothelial Growth Factor (VEGF), the prime anti-angiogenic dr
Seing the invisible, or, how to integrate metadynamics in the quantitative analysis of protein/protein complexes right at your fingertips. – METADYN
Molecular interactions play a key role in all the branch of analytical sciences. Among these interactions, those involving proteins are particularly fascinating as they comprise a large number of degree of freedom and are present in all biological processes. Indeed, a key feature defining protein fu
Two-dimensional Phase Transformation Materials – 2DTransformers
Structural phase transitions are ubiquitous in everyday's life and have given rise to various applications in information technologies and energy storage for instance. They exploit functional materials, whose properties change significantly upon a structural change, induced by a control parameter. T
Electrochemical Harnessing of Microbial Communities – El Hamico
El Hamico designs and validates an innovative, low-cost, on-site, and ecological bioremediation solution, suitable to sewer pipes, artificial channels and streams, and thus at improving the security and the quality of degraded urban river while lowering the bioremediation costs. El Hamico proposes a
Methane Efficient and Selective Oxydation Using Hemicryptophane Catalysts – MEUH
The aim of the MEUH project is to achieve the direct and selective oxidation of methane to methanol using catalysts confined in a supramolecular structure. This major challenge deals with crucial energetic and environmental issues of the XXIth century, since methane resources are estimated to be mor