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* Challenge for cornea banks Improving cornea endothelium quality control will improve the quality of selected grafts by avoiding overestimations in cell counts, that implies the grafting of corneas with an insufficient number of cells. It will also avoid the overestination, that implies the destru

There is a need of a convenient and robust non-invasive technique capable of accurately assessing the hydrational status of home-based patients with renal insufficiency. Techniques are available in the clinical setting to aid to detect and interpret variations in body composition associated with met

Development of a detector composed of, an X-ray absorber, a readout circuit, and of the corresponding output data processing, for patient constituents recognition (bones, soft tissues, contrast agents). The test circuit has been realized and is under characterization (see the results in correspondin

Osteoarthritis is a major cause of pain, disability and loss of autonomy in the elderly people. Life expectancy progressing, age while maintaining a physical activity without pain has become one of the main challenges. The management of knee osteoarthritis is a major public health issue. To provide

Diseases affecting small vessels (less than 150µm diameter) are important causes of morbidity and mortality from cardiovascular and cerebrovascular causes, alone or in association with diseases of large arteries. Predictive biomarkers are obtained from vascular imaging for large vessels. Research on

Anomalies in the execution of some movements including walking are found in the early stages of AD., A better understanding of sensorimotor impairments and effects on motion planning is needed to improve care for patients. In view of the difficulties observed in the use of explicit learning methods,

In industrialized countries, 20% of the working population is involved light work or shift work. It is in 2012 about 5 millions French people, and the number is increasing. Health consequences of shiftwork are well known, and recognized at the national and international level (OMS, HAS, Dares, Cons

AMNIFIR project is led by DIAFIR, a start-up company created further to the FIR-MED project of the “ANR emergence” program. The mission of the company is to provide minimally invasive and quick diagnostic systems. To do so, it develops a system based upon mid infrared spectroscopy, performed remot

As a result of ageing, of various life trauma/accidents and/or bone diseases (osteoporosis for example), the number of bone factures and trauma dramatically increases especially in the most industrialized countries where it raises a public healthcare issue. The number of bone graft procedures perfor

The sleep apnea syndrome (SAS) is a multifactorial disease characterized by repeated episodes of breathing pauses (apnea) or significant reduction of the respiratory amplitude (hypopnea) during the sleep of the patient. This disease affects more than 5% of the general population, but remains underdi

Over the last three decades, loss of autonomy associated to aging has become a major health issue due in particular to dementia and falls. Balance and gait troubles are sources of pronounced disability affecting durably and significantly quality of life. The prevalence of falls is even higher for ne

Percutaneous medical procedures, guided imagery or not, benefited from the contributions of localization tools and navigation. However, these tools remain imperfect. In the context of percutaneous procedures using a needle, we demonstrate that we can provide the physician augmented interventional en

Since almost a century electrical activities of hearth and brain have been visualized by electrocardiography (ECG) or electroencephalogry (EEG). Since three decades, these electrical activities of hearth and brain could also be visualized by fluorescent dyes. The general idea is to change the electr

Devising convenient and friendly Man-Machine Communication interfaces for restoring or augmenting cognitive abilities in patients or healthy humans is strongly needed in health and education. We recently discovered and tested a new device based on eye movement control that enables individuals to dra

Context Each year, about 400 000 patients in Europe and 500 000 in the USA have a Total Hip Athroplasty (THA). 13% of these surgeries lead each year to a hip revision surgery, with an average cost 35% superior to the primary procedure, and with a higher level of morbidity. Multiplying surgical p

The medical device market is experiencing growth in France and abroad. Several studies have shown that the global market for medical devices (DM) is in continuous progression. The process developed by CRITT-MDTS and INSERM Unit at the University of Reims is a real technical innovation because it is

Computerized medical records are a potentially very important source of information for fields ranging from assisted decision support and evidence-based medicine to epidemiological surveillance. As much of this data is available as unstructured text, natural language processing techniques can be use

The recurring loss of everyday objects is a problem which, when secondary to a cognitive impairment, constitutes a disability. In Alzheimer's Disease (AD), over 70% of the patients frequently loose valuable and/or essential everyday objects (glasses, wallet, dentures...). But this phenomenon, often

Osteoarthritis is an important public health issue. For humanistic and economical reasons, there are many reasons to identify and treat OA as early as possible. Knee Osteoarthritis (OA) is the most common rheumatic disorder. The most used methods are plain X-rays and Magnetic Resonance Imaging. New

Dependence (5th risk) is a major issue in our societies. This risk is related to several simultaneous phenomena: an aging population, increasing life expectancy, aging populations with disabilities, obesity, increased frequency of disabling disease with age, etc.. The inability to move is a componen