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Epigenetic dynamics of X-chromosome inactivation in the mouse – EpigenetiX
Rôle de TFiH dans la régulation de l'expression des gènes par divers récepte nucléaires – iHREGULATOR
1- Scientific background and objectives TFIIH is a multiprotein complex involved in both transcription as well as DNA repair. Mutations in its two largest subunits (XPD and XPB helicases) yield the rare autosomal recessive disorders, such as Xeroderma Pigmentosum (XP) and Trichothiodystrophy (TTD),
Microtubule organization and cellular pattern formation – MTOC function
Genetic and cellular regulation of stem to differentiated states in mouse skeletal muscle – Tajbakhsh
Scientific background and objectives: Stem cells are crucial for establishing and maintaining tissues and organs. Only rudimentary information is available on stem cell self-renewal and differentiation. This proposal aims to characterise stem cells and their daughters in skeletal muscle. One importa
Transcriptional antagonism between Ikaros and Notch: implications for T cell physiology and tumorigenesis – Ikaros - Notch
This proposal aims to dissect the molecular antagonism between the transcription factors Ikaros and Notch/RBP-Jk (the downstream mediator of Notch signaling) on the promoters of shared target genes, and the physiological consequences of this antagonism on differentiation versus transformation of T l
taille des pays et stratégies de croissance – TPSC
A mouse genetic approach to dissect the novel role of the calcineurin/NFAT signaling pathway in lymphomagenesis. – CalciNFAT
Cell surface receptors coupled to the activation of phospholipase C-g (receptor-type tyrosine kinases, immunoreceptors) or phospholipase C-b (G protein-coupled receptors) lead to the increase in intracellular calcium ion concentration through the sequential opening of specific calcium channels. The
COMPRENDRE LA MONDIALISATION COMMERCIALE (1830-2005) – RICardo
Processus mémoriels et textes hermétiques – PROMETHE
Dynamic of the Tip60 complex – ComplexTip
Structure of vacuum, topological strings and black holes – BHTSV
A STEP: an Antarctic Search for Transiting Extrasolar Planets – A STEP
Separator for Heavy ELement Spectroscopy – SHELS
Les processus biogéochimiques transitoires de la zone intertidale – PROTIDAL
Régulation Transcriptionnelle des Composants du Ribosome – TRANSRIB
Etude du rayonnement cosmique de très haute énergie (1-1000 TeV) – CREAM
Interactions complexe/symplectique : géométrie et dynamique. – SYMPLEXE
This project deals with the interaction between geometry and dynamics, which shows up as soon as there is some group action preserving some geometric structure. The groups that we have in mind are typically Lie groups, or lattices in Lie groups, or more generally, finitely generated groups. Several
Magnétohydrodynamic flows in Astrophysics and Geophysics using NumErical and Theoretical approaches – MAGNET
1 - Scientific background and objectives The MAGNET project has two main objectives. The first objective is to pursue the development of existing magneto-hydrodynamics (MHD) numerical codes (ideal-MHD and kinetic codes) to make them freely accessible on line, once extensively tested and fully doc
Information, Energy and the Efficiency of Professional Tennis Serves – TennisServer
Extended Molecular Buildings for Nitrogen-Atom Transfer – EMOBUNATT
New Developments in Business Cycle Analysis – NDBCA
Cold Reactions between Neutral Species – CRNS
TELEOS,Technology Enhanced Learning Environment for Orthopaedic Surgery. – TELEOS
Large scale Production of Integral Membrane Protein – IMPP
How is it to activate polycistronic translation in eukaryotes – APTAK
Cohesin dynamics during the cell cycle – cohesion
Peroxiredoxin regulation as a cross-talk between NO and H2O2 in mammals – NOperox
Energy loss of laser-accelerated high-energy ions in warm dense plasmas – ELAHI
Influence of mRNA structures on ribosome accuracy – RNA_RECOD
Powder Crystallograpy by High-Resolution Solid-State NMR of Protons – PSD-NMR
Cadherin-mediated signaling in myogenesis induction and myoblast fusion – Cadgenesis
From NO to OO an experimental approach – NO to OO
Constraint Acquisition aNd Automatic Reformulation – CANAR
Sediment Transport and Erosion Across Mountains – STREAMS
Dynamics, assembly and function of tetraspanin-enriched microdomains – Tetraspanins
Cell calcium signatures regulate plant phenypropanoid metabolic phenotype – Caphe
Local-Probe Induced Electrografting – LOCALGRAFT
Specificity of the molecular mechanisms involved in podosome dynamics – PODOSOMES
Theory and Application of Deep Inference – INFER
Accidents in Climate Carbon cycle Regulation of the Earth – ACCRO-Earth
Cellular and Molecular Mechanisms controlling Left-Right Asymmetry – CaMMeLeRiAs
Regulation of muscle morphogenesis by the Planar Cell Polarity pathway – MUSCLE&PCP
ENDO SYMBiosis in ARThropods – ENDOSYMBART
AICAR-SAICAR : small molecules, big effects – AICAR
Telomere length regulation : from molecular controls to cell fate – TELOREG
Control of cellulose synthesis in higher plants – IMACEL
Replication of Damaged DNA in Human Cells – HumanBypass
Bifunctional ligands: a joint experimental / theoretical approach – BILI
Multiscale modeling: from Electromagnetism to the GRID – MEG
1- contexte scientifique et objectifs du projet In the field of Sciences and Technologies for Information and Communication, there are key scientific challenges to develop miniaturized systems embarking more and more intelligence both at the physical and the software layer, with architectures increa
New vibrational probes of biological edifices – PROBIO
Fronts, secondary cycLOnes and gravity Waves: Instability and traNsport – FLOWINg
Giga Hertz Optically-Controlled Piezo-Electrical Transducers – GHzOCPETs
Environments of Early Life on Earth – eLIFE
Functional and structural mechanism of multidrug ATPase pumps – MDR ATPases
Evaluation of Redistribution Policies by Simulation Techniques – MICROSIMULA
HOLMES (Hunting cOol Low Mass Extrasolar PlanetS) – HOLMES
Pulsatile magnetically driven pump for mechanical circulatory support – PULSAMAG