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Environmental ePIdemiology of COVID-19 in French Guiana: combining eDNA and biogeography to forecast future epidemiological waves
Since its emergence in Wuhan, China in 2019, the speed of the spread of the Covid-19 pandemic, coupled with a lack of scientific and medical knowledge, underscores the need to improve our understanding of the epidemiological dynamics of SARS-CoV-2 within the population. In addition to the need to qu
Seroprevalence of IgG antibodies to SARS-CoV-2 in primary health care workers and their household contacts.
Current knowledge regarding the level of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunity is mainly based on mathematical modeling, and most reports describing the prevalence of the infection are focused on inpatients and/or hospital health care workers (HCWs). However, to our k
Consequences of the timing the of type I interferons response on the clinical course and immune response to SARS-CoV-2 infection.
Type I interferons are the main antiviral cytokines. They stimulate the expression of antiviral effectors and regulate the activation of various immune cells. However, type I interferons may not always be beneficial during a viral infection, as they can cause an excessive inflammation leading to imm
COVID-19 and innate immune response : dysregulation of phagocyte functions during SARS-CoV2 infection
First COVID-19 studies have pointed out an abnormal immune response in patients, particularly in severe cases. High concentrations of proinflammatory cytokines and chemokines, high number of neutrophils with low number of lymphocytes have been associated with the main causes of adverse outcome such
French universities facing COVID
Research on organizational crisis management focuses almost exclusively on nuclear power plants, industrial sites at risk or the reactions of public administrations to disasters. But how do organizations behave which, like universities, are characterized by functional loose coupling and weak technol