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Daycare environment, nasal microbiota, and respiratory health in young children – CRESMINA
The CRESMINA project focuses on daycare centers, an environment in which many young children spend a large part of their time and which may influence the risk of asthma. The main objective is to study the relationships between the daycare environment, the nasal microbiota, and respiratory health in
Dynamic Models for Epidemiological Longitudinal Studies of Chronic Diseases – DyMES
DyMES aims at developing and applying innovative statistical methodologies to improve the understanding and prediction of multivariate dynamic health phenomena. The project focuses on two neurodegenerative diseases, Alzheimer's disease (AD) and multisystem atrophy (MSA), which share major methodolog
Telling, Hearing and Reporting Incestuous Violence – DERVI
Despite public condemnation, incestuous violence persists: 5 to 6% of children are victims of sexual assault by a family member. At the crossroads of socio-historical, legal and anthropological studies, the multidisciplinary research project DERVI will take up the issue of incest by focusing, in an
viruses to cure: the difficult development of a counter-intuitive biomedical innovation – anthropo-phages
This project aims to conduct interdisciplinary reflection on the therapeutic use of bacteriophage viruses (or phages) to treat human bacterial infections. Faced with the rise of antibiotic-resistant bacteria, considered by the World Health Organization (WHO) as one of the major public health challen
Optimization of Personalized Treatments – OPT
Personalized or precision medicine aims at giving the “right treatment to the right patient”. It is one of the most promising areas of medical research, but its development is hindered by methodological limitation of studies used. Determining individualized treatment rules (ITR) is an active researc
Social inequalities of health in urban context at the time of major socioeconomic changes: looking at individual and neighborhood determinants in the Greater Paris area – SIRS-4
The SIRS survey (Santé, Inégalités et Ruptures Sociales – Health, Inequalities and Social Disruptions) aims at investigating the social and territorial determinants of health in the Greater Paris area. It includes 3000 people and constitutes a representative sample of the adult population living in
Stuttering: neurology, phonetics, computer sciences for its diagnosis and its reeducation – BENEPHIDIRE
This project aims at providing supplementary knowledge on stuttering, in order to help with its diagnostic and speech therapies. The project involves a multidisciplinary team including researchers in linguistics, computer science and neurology on the one hand, and, on the other hand, speech-language
What is driving changes in twinning in the developed countries? – JUMEAUX
In developed countries the twinning rate has increased tremendously (almost two-fold) since the 1970s. This increase is an important public health issue because twin babies are more fragile than singletons, due to their low birth weight, their tendency to be born premature, and complications at birt
Risk factors of Parkinson disease among women from the E3N cohort – PARKIN-WOMEN
Parkinson's disease (PD) is the second more frequent neurodegenerative disease after Alzheimer’s disease. It is about 1.5 times more frequent in men than women who are exposed to estrogens throughout their life, from puberty to menopause, and eventually after through postmenopausal hormone therapy (
Prenatal Exposure to Tobacco smoking and Air Pollution and Effects on offspring respiratory and neurodevelopmental outcomes: role of placental DNA methylation – ETAPE
Several Mechanisms are suspected to explain these effects and epigenetics is likely one of them. DNA methylation has been associated with a range of exposures and health outcomes, including maternal exposure to tobacco smoking and air pollution as well as respiratory health and neurodevelopmental ph