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Ehlers–Danlos syndrome (EDS) periodontal-type (EDS-VIII) is a connective-tissue disorder characterized by aggressive periodontitis and various joint and skin manifestations. It is inherited as an autosomal dominant trait. In 2003, a genetic study on three families established linkage to an interval

Nucleo-cytoplasmic transport through nuclear pores is an essential and tightly regulated process in eukaryotic cells. Proteins and multi-component complexes are recognized by transport receptors, called karyopherins. Cargo-receptor interactions are highly specific to ascertain that only fully assemb

Anti-neutrophil cytoplasmic auto-antibodies (ANCA) associated small vessel vasculitis (AAV) is an acute inflammatory disorder characterised by rapid and often irreversible organ failure. Initial injury is, in the presence of ANCA, initiated by inflammation leading to vessel wall necrosis of small-to

Platynereis is a segmented worm easily reared in the laboratory and amenable to genetic engineering techniques. In recent years, a series of remarkable publications have shown that Platynereis is a "short branch" organism that has kept a number of ancestral-looking characters at the genome, anatomic

This project focuses on the isolation and characterization of unknown genes involved in the formation of higher hydroxylated flavonols, which serve as yellow flower pigments and UV-honey guides in the Asteraceae family. Higher hydroxylated flavonols carry additional hydroxyl groups in positions 6 an

The project investigates the foundations of the “operational” approach to quantum probabilities. Though the effectiveness of this approach is widely acknowledged by physicists, much less consensus exists about its logical consistency – whence the low popularity of Bohr-inspired instrumentalist inter

Our investigation focuses on the proof theory of logics that are variants and generalizations of modal logic, including: normal and non-normal modal logics, conditional logics, bunched implication logics and substructural logics. We study formal proof systems with the analyticity property, as they a

The overall aim of this project is to deepen the understanding of the factors determining DNA repair pathway choice and the outcomes of recombinational repair at somatic and meiotic DNA double strand break (DSB) sites in plants. It thus focuses on understanding the fundamental genetic mechanisms ens

This project of an Austrian-French research collaboration is aimed at exploring, in a joint experimental and theoretical effort, the dynamics of impurities inside quantum wires of ultracold atoms. Mobile impurities inside a host medium constitute a paradigmatic physical system in condensed matter ph

Hydrogen, the simplest of all atoms, forms the stable and well-known diatomic hydrogen molecule, H2. Hydrogen also forms a very stable triatomic positive ion, H3+, which is a very important ingredient for interstellar molecular clouds and has been studied for many years. It is much less well know

The essential building block of visualization is the phenomenon of visual abstraction. While visual abstraction is intuitively understood, there is no scientific theory associated with it that would be useful in the visualization synthesis process. Our central aim of this project is thus to gain bet