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“interesting” target state, both of which are crucial features for adiabatic quantum computing. It is expected
Revealing the impact of centromeric DNA on centromere formation, integrity and function – CENtegrity
centromeric regions. These alterations are common features of cancer cells and developmental disorders.
Understanding Fine Scale Processes <br />in Intense Sediment Transport Regimes <br /> <br />Fine-scale processes such as turbulence-particle and particle-particle interactions may be of prime importance for sediment flux dynamics. A new class of models, capable of tackling this issue exists but their development is limited by the lack of detailed high-resolution experimental data. Providing these missing data for developing innovative sediment transport models is at the core of the present project.
To a first approximation, all species are extinct, and those that are not are still unknown. This hidden biodiversity is or has been involved in horizontal gene transfers, just like the biodiversity that we know. <br />By detecting genes that have been horizontally acquired in genomes that we can analyze, this project proposes to detect species that are still unknown but that have been hosts of these genes at some point.
Working in the margin? Collaborative spaces as nodes of a new mobility system outside metropolis – PERI_WORK
Collaborative workspaces as nodes of a new mobility system outside metropolises
Our aim is to understand the role of pathogenicity factors of plant-pathogenic fungi, called effectors, in the infection process and in changes in virulence after host-shifts. Our central hypothesis is that the first step of host-shifts (the fixation of immune-escape mutations enabling to overcome non-host resistance) is followed by a second step of fine-tuning during which effector variants that efficiently interact with their target proteins in the novel host species are selected.
Several threats endanger the tight equilibrium between genome maintenance and expression that guarantees nuclear homeostasis. Among them, the formation of R-loops through hybridization of nascent mRNAs onto their DNA templates has emerged as a major cause of transcription-associated genetic instability. However, the molecular mechanisms involved in R-loop sensing and processing in space and time remain to be deciphered.
The LightNing project aims at developing the first generation of LnNi(II)X2 precatalysts that could be cleanly, effectively and selectively photoreduced into well-defined and catalytically active Ni(I)/Ni(0) species.
To explore and interpret the behaviours of populations of confluent spindle-shaped cells confined in mesoscopic tracks and subjected to an external field.
The aim of this project is to consider the impact of job complementarities in employment on segregation, inequality, and social mobility. The degree of complementarity between different categories of workers is a key dimension determining labour market outcomes. These complementarities evolve over time. It is hence important to understand who works with whom (at the level of the firm, the city, the region or the household) if we want to explain the labour market performance of minorities.