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Conception, synthèse et études métaboliques de nouveaux pièges pour la détection de radicaux libres dans les systèmes biologiques – SPIN BioRad
Developments in the spin trapping / EPR technique for the detection and the characterization of free radicals in biological systems.
Synthèse de nouveaux nitroxides pour le diagnostic et l'étude de pathologie chez le petit animal via l'activité des protéases vue par IRM et effet Overhauser. – NITROMRI
No non-invasive spectroscopic techniques as efficient as MRI and suitable to monitor the enzymatic activity in tumors are available. This project aims to develop a new technique of MRI: the Overhauser-enhaced MRI which amplifies the conventional signal and is suitable for investigating in vivo the enzymatic activity.
SPIRolactones from ALkylidene butenolides : An efficicient entry towards the preparation of complex highly oxygenated polycyclic structures – SPIRAL
Synthesis of spirolactone moities from alkylidene butenolides : an efficient entry towards the preparation of complex highly oxygenated polycyclic structures
Superinsulating sol-gel silica are very promising for thermal superinsulation at atmospheric pressure. However, new solutions need to be developed in order to overcome their mechanical weakness. Resorting to hyperporous cellulosic structures is one of the most pertinent solutions conceivable, as this approach allows reaching aforementioned improvement without augmenting the silica's environmental impact.
Re-evaluation of the synthetic potential of nitroarenes: Fast access to complex polysubstituted aminocompounds of high added value.
reactivity, structure, morphology, and electrochemical features of these compounds. A real alternative for the
estimation and the ancestral genome size; both features (ancestral gene number/order and genome size)
Variations in reproductive activity are common feature among seasonal mammals including sheep. Photoperiod
physiopathological conditions. One of the original features of this project is to combine a unique in vivo