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Learning causal effects between phenome and exposome from large amounts of heterogeneous data in human complex diseases – GePhEx
Learning causal effects between phenome and exposome from large amounts of heterogeneous data in human complex diseases.
The characterization of the mode of action of the PBP regulators studied in this project will contribute to a better understanding of the inner-workings of bacterial cell morphogenesis. In applied terms, it will open new avenues towards the rational design of new antibacterial drugs and new strategies to combat bacterial infections, notably antibiotic resistant-strains.
PARAMOUNT: Production of Aerosol paRticle orgAnic Matter in ClOUds: chamber and laboratory studies, mechanisms, modelling and iNTegration – PARAMOUNT
Demonstrate how and quatify how much the cloud processes contributes to the atmospheric organic aerosol burden.
Chirped Pulse And Resonator In one Spectrometer: A novel combined molecular jet chirped pulse/cavity Fourier Transform MicroWave spectrometer for fast scan, high-resolution, and chiral discrimination – PARIS-FTMW
The chirped Pulse And Resonator In one Spectrometer (PARIS) applies an innovative and resource-efficient approach: Using a smart design, most electronic components are used in a dual-purpose spectrometer while almost all vacuum equipment are shared. Therefore, PARIS is built at much lower costs than two individual spectrometers and exceeds the advantages of both techniques individually: Rapid broadband capabilities, intensity reliability, as well as unrivalled resolving power and sensitivity.
Innovation and Transformation for<br />Prevention Activity of Professional Risks
Acoustic impact of ship traffic on mussels and scallops of the Gulf of Saint Lawrence
Polycomb Repressive Complex in Paramecium: interaction with small RNA machinery and substrate specificity – POLYCHROME
Polycomb Repressive Complex 2 (PRC2) trimethylates histone H3 on lysine 27 (H3K27me3), catalyzed by the Enhancer-of-zeste lysine methyltransferase subunit. Despite intensive research, the mechanisms that regulate the activity of the Polycomb complex and control its targeting remain largely enigmatic and are the focus of our research program POLYCHROME.
Asthma is a frequent disabling chronic respiratory disease associated with high global costs. For two environmental factors, respiratory allergens and respiratory viruses, strong association with asthma incidence or exacerbations is well documented. A few previous observations suggest that the host genotype plays an important role in the immune response of individual allergens and rhinovirus, but these studies were limited in the assessment of allergen-specific and RV-specific immune responses.
The aim of this project is to explore and to develop radically new material systems based on AlN ultra-wide bandgaps for future power devices providing higher robustness and superior temperature operation towards the ultimate all-binary AlN/GaN/AlN heterostructure. The AlN material will enable high efficiency operation beyond 1200 V as well as higher power performances in the millimeter-wave range, which is not currently reachable by GaN devices.