CE51 - Sciences de l’ingénierie et des procédés

Multiscale Smart Texturing of Medical Implants – MustImplant

Submission summary

The MUST Implant project brings together 4 academic research laboratories which pool their skills for innovating a new concept in the field of surface science: the Multiscale Smart Texturing. Taking account quantitatively a huge set of data met in the bibliography, the concept consists in designing optimal functional surface thanks to an original methodology based on a new Knowledge Management tool. This generic surface texturing approach will be applied in the field of smart texturing of endosseous implants for increasing their performance and safety. The 25 years’ collaboration of 2 academic partners of this project and their advanced understanding of the influence of surface topography on bone cells will allow them to design optimal topographies. After manufacturing of implants with these optimal topographies through innovative Femtolaser-based manufacturing techniques, they will be mechanically, chemically and biologically tested to provide proof-of-concepts and validate osteoconductive topographies at the end of the project.

THE CHALLENGE: IS THAT POSSIBLE TO DESIGN AND TEXTURE BY FEMTO-LASER AN OPTIMAL SURFACE TOPOGRAPHY OBTAINED BY BLENDING A SET OF EXISTING SURFACES TOPOGRAPHIES KNOWN FOR THEIR HIGH BIOLOGICAL FUNCTIONALITIES ?

Numerous in vitro and in vivo studies have demonstrated the role of topography on bone cells but also on the implant anchoring in bone tissue. However, the definition of the best topography to promote the anchoring of implants in bone tissue is still currently carried out empirically. Our ambition in this project is to propose a knowledge capitalization approach for a smart texturing of medical implants.

Project coordination

Maxence BIGERELLE (Laboratoire de Spectroscopie pour les Interactions, la Réactivité et l'Environnement)

The author of this summary is the project coordinator, who is responsible for the content of this summary. The ANR declines any responsibility as for its contents.

Partner

Université de Lille
LTDS Ecole Centrale de Lyon
IS2M Centre national de la recherche scientifique
LAMIH Laboratoire de Spectroscopie pour les Interactions, la Réactivité et l'Environnement

Help of the ANR 609,986 euros
Beginning and duration of the scientific project: September 2022 - 48 Months

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