DS04 - Vie, santé et bien-être

Fast Single-Pixel Biomedical Imaging – Armoni

Submission summary

Recent advances in signal processing have made it possible to design new digital imaging systems. Single-pixel imaging is a new paradigm that enables two-dimensional imaging from a point detector. It has raised increasing attention because it allows high-performance optical imaging systems (e.g., hyperspectral and/or time-of-flight measurements) at very low cost. Single-pixel cameras comprise a single point detector that is coupled with a spatial light modulator. By performing a sequence of optical measurements for different modulation patterns, it is possible to recover the image of the observed scene provided that ad-hoc restoration algorithms are implemented.
The main goal of this Project is to demonstrate the feasibility of fast single-pixel biomedical imaging.
Single-pixel imaging will be of particular relevance in image-guided surgery, where the optics are relatively easy to implement, and it is safe for both the surgeon and the patients, unlike to ionising modalities. Single-pixel imaging can provide functional information on the state of the tissues. However, current single-pixel cameras are two slow to operate in real time, which precludes their applications to this field.
In this Project, we aim to develop a single-pixel video acquisition set-up together with dedicated algorithms to image with 1024 × 768 resolution at 10 Hz, which is 10--100 times faster than the state-of-the-art approaches. To meet this objective, we will focus on the development of adaptive acquisition-reconstruction approaches that provide a fast alternative to compressed sensing, as demonstrated in our recent studies.
Our solution will be evaluated in neurosurgery, where fluorescence imaging is already used routinely to guide the surgeon. This project should provide proof of concept for single-pixel imaging used as an imaging tool in fluorescence-guided surgery.
Moreover, the optical devices routinely used in operation theatres do not exploit all of the available information. In particular, photon time-of-flight and full spectrum are usually not captured. Beyond cost reductions, single-pixel cameras coupled with spectrometers and/or time counting single pixel counting boards could improve current imaging techniques.

Project coordination

Nicolas DUCROS (Institut National des Sciences Appliquées de Lyon - Centre de Recherche en Acquisition et Traitement d'Images pour la Santé)

The author of this summary is the project coordinator, who is responsible for the content of this summary. The ANR declines any responsibility as for its contents.


INSA LYON - CREATIS Institut National des Sciences Appliquées de Lyon - Centre de Recherche en Acquisition et Traitement d'Images pour la Santé

Help of the ANR 289,163 euros
Beginning and duration of the scientific project: September 2017 - 48 Months

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