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Genome Interactions and Malaria transmission Efficiency in Anopheles gambiae – GIME
Our project aims at investigating the impact of the mosquito aquatic environment on its vectorial capacity and particularly the role of bacterial communities present in larval habitats and mosquito midguts.
Mind in meaning construction: Reference markers, prosody and gesture – MINDPROGEST
to establish that this ability is a fundamental feature of human cognition. While loads of researches [...] and recognition of intentions is an essential feature of human communication (Grice, 1957) implying that
Comparative analysis of signal transduction factors controlling cell cycle regulation in the alpha-proteobacteria – CASTACC
In the bacterial model species Caulobacter crescentus and Sinorhizobium meliloti the cell cycle, that is the coordination of DNA replication and asymmetric cell division, is controlled by a complex circuit composed by many regulators. In the project CASTACC, the two regulatory networks of these two species are compared using a multidisciplinary molecular approach.
Structural, mechanistic and inhibitor design studies of the Bunya- and Arenavirus L-proteins – ArenaBunya-L
Arenaviridae, Bunyaviridae and Orthomyxoviridae are segmented negative strand single-stranded RNA viruses and include many serious and/or emerging human pathogens (e.g. Lassa Fever, Crimean-Congo Hemorrhagic Fever and Influenza viruses). For arena- and bunyaviruses, transcription and replication of the viral genome segments is performed by the single chain RNA-dependent RNA polymerase (RdRP) or L-protein, which is functionally similar to the hetero-trimeric influenza polymerase complex.
Multi-functional memory elements using supramolecular self constructing interconnects – MultiSelf
The self-assembly of supramolecular architectures is used for realizing organic conductors with metallic properties, allowing us to test the possibility of transferring the spin information of the charge carriers, which can be modified through the electric, magnetic , or electromagnetic field. Novel devices can thus be realized.
Chemistry with quantum Monte Carlo – QMC=Chem
The aim of the QMC=Chem project is to develop an original simulation method allowing to use the computer as a virtual chemistry laboratory. This is made possible thanks to the overwhelming performance of supercomputers.
Kinetically-tunable self-immolative aromatic spacers – KITUSE
After a photoactivation step, one or more bioactive compounds or fluorescent reporters will be released through the use of a self-immolative spacer.
MRAM (Magnetic Memory) based Architecture for Reliable and low power Systems – MARS
the advent of memory technologies combining new features (non-volatility, density, performance, low power
Architecture for MObiquitous REsilient Systems – AMORES
data that we coin as locanyms. To offer such features, the geo-primitives require some basic components