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Implementation of a fast and reliable assay for the high-throughput screening of antiviral molecules active against SARS-CoV-2 – Alpha-COV
Syndrome Coronavirus 2 (SARS-CoV-2) has led to an unprecedented pandemic termed Covid-19 (Coronavirus disease
Inborn errors of immunity underlying life-threatening COVID-19 in previously healthy patients – GENCOVID
In December 2019, a pneumonia due to a novel coronavirus (SARS-CoV-2) emerged in the city of Wuhan, China [...] ranging from asymptomatic infection to lethal coronavirus infectious disease-19 (COVID-19). Two groups
Inhibition of SARS-Cov2-S - ACE2 interaction AS A THERAPEUTIC TARGET – ACE2-S-Cov
Coronavirus disease 2019 (COVID-19), which is caused by the recently discovered severe acute respiratory [...] respiratory syndrome coronavirus 2 (SARS-CoV-2), has become pandemic, in the absence of an approved drug treatment [...] virus surface spike protein (S), which mediates coronavirus entry into the cell, is an attractive target
Inhibition of coronaviruses infections using innovative nanostructures – NanoMERS
The main goal of the NanoMERS project is the identification of specific and efficient nanomaterials derived anti-MERS-CoV agents effectively inhibiting viral entry and their in vitro and in vivo testing. The focusis on the use of carbon based nanostructures, notably modified C-dots and graphene-dots and nanoparticle formulations of poly(D, L-lactide-co-glycolide) (PLGA).
Interventions for Covid-19 infection: a living mapping of research and a series of living network meta-analyses – living-NMA-covid
Context: In December 2019, a novel coronavirus outbreak was documented in Wuhan, Hubei Province, China [...] first 6 weeks of the new decade, this novel coronavirus, known as SARS-CoV-2, has spread from China to
Involvement of circulating fibrocytes in pathophysiology and prognosis of COVID-19 pneumonia – FIBROCO
High circulating levels of fibrocytes are correlated to an unfavourable outcome during acute respiratory distress syndrome (ARDS) and idiopathic pulmonary fibrosis. COVID-19 pneumonia shares common histological and inflammatory features with ARDS. We aimed to determine the involvement of circulating fibrocytes during the course of COVID-19 pneumonia, and to assess if fibrocytes could be a prognosis biomarker.
Lung cell senescence as a target to combat COVID-19 – SENOCOVID
The new coronavirus disease 2019 (COVID-19) due to infection by severe acute respiratory syndrome coronavirus
Mitochondrial and metabolic evaluation of COVID-19 patients: new predictive factors and therapeutic targets – MIMETIC
Since last December, the coronavirus disease 2019 (COVID-19) affected more than 23 million people, causing
Modulation of SARS-CoV-2 cell entry – COVENTRY
COVID-19 pandemic is due to the SARS-CoV-2 coronavirus that infects human cells through binding of its
Molecular role of the viral nucleoprotein in the SARS-Cov-2 replication cycle – SARS2NUCLEOPROTEIN
inhibitors of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) it is essential to understand [...] basis of different aspects of the viral cycle. Coronaviruses are enveloped positive-sense single strand RNA