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Genome-wide CRISPR screens for drug target identification and inhibition of SARS-CoV-2 replication – CRISPR-TARGET-CoV
y syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of the current coronavirus disease 2019 [...] global economic crisis. SARS-CoV-2 is the seventh coronavirus identified as capable of infecting humans and
Identifying SARS-CoV-2-like and other coronaviruses able to infect humans in bats from Indochina peninsula – BAT-CoV-ASIA
objective of the project is to identify bat coronaviruses close to SARS-CoV-2 and other alpha and bet
Emergence dynamics of Sarbecovirus coronaviruses : Zoonose mecanisms. – EmerCoV
virus Sarbecovirus (SARS-CoV2, the COVID-19 coronavirus) which emerged in humans in similar circumstances [...] provide a better understanding of bat-borne coronavirus emergence in a changing world.
Autoantibodies against type I IFNs in Lebanese patients hospitalized with COVID-19. – AAILC
Since 2003, three coronaviruses, SARS, MERS, and SARS-CoV-2, have led to devastating pandemics. Although [...] vaccines are available, new variants and even new coronaviruses could emerge at any time. Understanding the
Identification of SARS-CoV-2 RNA ibinding proteins durig viral replication – CoV-2RBP
caused by a novel coronavirus (CoV), the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Engineering nanobinders to block SARS-CoV-2 entry – SARS2BlockEntry
The novel coronavirus SARS-CoV-2 has recently emerged as a human pathogen in China’s Hubei province, [...] high-titer neutralizing antibodies in others coronaviruses and to fold independently from other spike domains
NSP3 polyprotein of SARS-CoV2: structural studies and its exploration in drug screening campaign – COVNSP3
alarming emerging infectious disease caused by coronavirus (CoV). The current COVID-19 pandemic, which [...] Wuhan region of China, is caused by a novel coronavirus, SARS-CoV2 which is more infectious than the
LabCom PHYTOMAR’INNOV – PHYTOMAR
polyphenols for the prevention of coronavirus infection. The coronaviruses responsible for three epidemics
Identification of novel inhibitors against emerging human coronaviruses SARS-CoV and MERS-CoV from host cellular transcriptionic signatures – CoV-SigN
In 2012, a novel human coronavirus (MERS-CoV) was identified in the Middle East as the causative agent [...] and community clusters. Emergence of this new coronavirus in humans raises concerns about a possible widespread [...] required to fight against these emerging hazardous coronaviruses adequately. In this context, the main objective
Inhibition of coronaviruses infections using innovative nanostructures – NanoMERS
The main goal of the NanoMERS project is the identification of specific and efficient nanomaterials derived anti-MERS-CoV agents effectively inhibiting viral entry and their in vitro and in vivo testing. The focusis on the use of carbon based nanostructures, notably modified C-dots and graphene-dots and nanoparticle formulations of poly(D, L-lactide-co-glycolide) (PLGA).