Synthèse Organique : des molécules au vivant

SynOrg LabEx (2012), Molecules for life sciences, is the research component of the research training innovation triptych, certified by the PIA in the field of organic chemistry in Normandy with the XL-Chem Graduate school (label 2019) for the "training" component, and I2C Carnot for the innovation component (Full Carnot in 2020). Synorg is the largest group of french organic chemistry laboratories in a territory which is the first basin of development and production of pharmaceutics in Europe. Labex Synorg relies on the skills of Norman researchers and Centre Val de Loire in five differentiating strategic axes recognized for their excellence at national and international level: innovation in analytical chemistry , heteroelement chemistry, chemistry mediated by metals, glycochemistry and heterocycles.

Important scientific breakthroughs were made in 2025 allowing to increase the international visibility in particular through the publication of articles in high impact newspapers and for some of them within the framework of international collaborations with renowned research groups (Léonori’s group, Montbaliu’s group, Waser’s group and Xu’s group). As a selection of lead papers in the field of health, we can mention :

- Excited-state configuration of nitroarenes enables oxidative cleavage of aromatics over alkenes (published in Science).

- Designing new natural-mimetic phosphatidic acid: a versatile and innovative synthetic strategy for glycerophospholipid research (published in Angew. Chem. Int. Ed).

- α-Amination of 1,3-Dicarbonyl Compounds and Analogous Reactive Enolate-Precursors Using Ammonia Under Oxidative Conditions (published in Angew. Chem. Int. Ed).

These publications with renowned research groups demonstrate SynOrg's commitment to establishing very high-level international research collaborations.

In 2025, SynOrg published 109 publications. Moreover, researchers from SynOrg participated to the writting of 12 book chapters. 3 patents were also granted in 2025.