CE07 - Chimie moléculaire

Compartmentalized Enantioselective MultiCatalysis – CoMuCat

Submission summary

Enantiomers physical separation starting from a racemic mixture remains a major challenge in modern chemistry from an academic as well as industrial point of view, given the few existing solutions. Indeed, these solutions are composed of either a separation based on physical principles, or indirectly by enantioselective or diastereoselective reactions requiring additional separation and transformation steps. The CoMuCat project aims to bring an alternative answer to this problem combining the enantioselective multicatalysis with a physical separation using modified membranes. In the envisioned scenarios, several catalyzed reactions are done in compartmentalized reactors separated by a membrane able to allow a selective diffusion of chemical species based on their polarity. A first task is dedicated to the modulation of the membrane permeability by surface and/or core modifications. A second task aims to elaborate new compartmentalized multicatalytic systems leading to the physical separation of enantiomers starting from a racemic mixture using membranes elaborated in the first task. Two processes are envisioned to reach this goal. The first allows the compartmentalized production of enantiomers, while the second aims to separate enantiomers from racemic substrates. Each of these processes leads to enantioenriched mixtures isolated in the dedicated compartments.

Project coordination

Cyril BRESSY (Centre National de la Recherche Scientifique Délégation Provence et Corse_Institut des Sciences Moléculaires de Marseille)

The author of this summary is the project coordinator, who is responsible for the content of this summary. The ANR declines any responsibility as for its contents.


CNRS DR12_ISM2 Centre National de la Recherche Scientifique Délégation Provence et Corse_Institut des Sciences Moléculaires de Marseille
IM2NP Institut des Matériaux, de Microélectronique et des Nanosciences de Provence

Help of the ANR 481,061 euros
Beginning and duration of the scientific project: December 2022 - 42 Months

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