CE07 - Chimie moléculaire

Axially chiral aryl-quinolones: atroposelective construction and applications in catalysis – QuinoA

Submission summary

Axially chiral molecules are not only common structural subunits in a vast array of natural products and biologically active molecules but they are also key components for stereoselective transformations in which they act as chiral inductors (ligands or catalysts). While elegant strategies have allowed the preparation of diversely functionalized enantioenriched biphenyl, phenyl-naphthyl and binaphthyl architectures, examples of enantioselective synthesis of aryl-heterocyclic atropisomers remain far less described. In a first part, the QuinoA project aims to develop new atroposelective cascade sequences for the construction of axially chiral aryl-quinolone architectures. The second part of the project will be devoted to the use of these molecules as promoters in asymmetric catalytic oxidation processes.

Project coordination

Xavier Moreau (Université Versailles Saint-Quentin-en-Yvelines)

The author of this summary is the project coordinator, who is responsible for the content of this summary. The ANR declines any responsibility as for its contents.


CEISAM Nantes Université
COBRA Université Rouen
ILV Université Versailles Saint-Quentin-en-Yvelines

Help of the ANR 428,016 euros
Beginning and duration of the scientific project: September 2022 - 48 Months

Useful links

Explorez notre base de projets financés



ANR makes available its datasets on funded projects, click here to find more.

Sign up for the latest news:
Subscribe to our newsletter