CE06 - Polymères, composites, physico-chimie de la matière molle

Antibacterial and Thermosensitive Macromolecular Coatings for the Release of Healing Agent on Chronic wounds – ARHES

Submission summary

Wound healing is a complex process aiming at maintaining the barrier function of skin. Failing to achieve sufficient healing, chronic wounds lead to persistent infections and the inability of skin cells to repair resulting in significant discomfort and distress of the patient. After removal of non-viable tissue material, the applied wound dressing can be exploited as a platform to deliver bioactive molecules to prevent bacterial infection and promote wound healing. ARHES project has the aim to develop thermoresponsive polyarginine coatings for the functionalization of wound dressings. The thermoresponsive coatings will possess three properties: (i) bactericidal by contact-killing thanks to polyarginine, (ii) antioxidant and (iii) the stimulation of wound healing both thanks to the release of a natural healing agent.

Project coordination

Fouzia Boulmedais (Centre national de la recherche scientifique)

The author of this summary is the project coordinator, who is responsible for the content of this summary. The ANR declines any responsibility as for its contents.

Partner

CMC Université Strasbourg
BioMat Institut national de la sante et de la recherche medicale
I.C.S Centre national de la recherche scientifique

Help of the ANR 460,934 euros
Beginning and duration of the scientific project: March 2023 - 48 Months

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