Plant tolerance to RNA viruses: molecular and genetic determinants – GreenTolerance
Viral diseases cause severe damage to cultivated crops. By contrast, wild plants are often ‘tolerant’: i.e., free of disease symptoms, despite recurrent infection. Tolerance is a defense strategy that optimizes plant fitness while allowing the virus to propagate; this differs from plant resistance, which exerts selective pressure and can cause the virus to escape the defenses. The determinants of plant tolerance to RNA viruses are poorly understood. Using two viral pathosystems with different Arabidopsis ecotypes, the GreenTolerance project combines the efforts of three partners with complementary expertise in virology, molecular biology, genetics and genome-wide association to identify plant genes for tolerance and study the molecular mechanism. Climate change, ecosystem disruption and insect proliferation are all predicted to alter virus-host interactions and the spread of viruses. Understanding the molecular basis of natural tolerance will help breeders to engineer virus-tolerant, disease-free crop plants.
Monsieur Manfred HEINLEIN (Institut de biologie moléculaire des plantes (UPR 2357))
The author of this summary is the project coordinator, who is responsible for the content of this summary. The ANR declines any responsibility as for its contents.
IBMP 1 Institut de biologie moléculaire des plantes (UPR 2357)
INRAE BFP Biologie du Fruit et Pathologie (UMR 1332)
IBMP 2 Institut de biologie moléculaire des plantes (UPR 2357)
Help of the ANR 720,009 euros
Beginning and duration of the scientific project: January 2022 - 48 Months