CE02 - Terre vivante

Diversity, lifestyle and evolution of the phylum Dependentiae in their associated protist hosts – DEPEND

Submission summary

Most bacterial taxa are yet-to-be cultivated, thus forming the ‘Microbial Dark Matter’ (MDM), a consortium whose ecology and biology remain largely unexplored. The Dependentiae are a major MDM phylum, found worldwide in various environments. Genomic evidence suggests an ancestral and unusual adaptation of all Dependentiae to a host dependent lifestyle with protists. However, the Dependentiae still remain to this day a poorly documented phylum. Thus, the Dependentiae stands as a model for investigating MDM, which the present project proposes to study for furthering the knowledge on such elusive bacteria. To this aim, 3 work packages will be developed, focusing on Dependentiae for characterizing: 1) Their host spectrum and environmental tropism 2) Their lifecycle (from selected isolated) using systems biology 3) Their genomic evolutionary history and processes in adaptation to their hosts.

Project coordination

Vincent Delafont (Ecologie et biologie des interactions)

The author of this summary is the project coordinator, who is responsible for the content of this summary. The ANR declines any responsibility as for its contents.


EBI Ecologie et biologie des interactions

Help of the ANR 309,008 euros
Beginning and duration of the scientific project: January 2022 - 48 Months

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