CE07 - Chimie moléculaire

Gold Catalysis under Visible Light – LuxOr

Submission summary

Gold(I) catalysis is very efficient to promote the electrophilic activation of C-C multiple bonds. The resulting organold intermediate generally undergoes protodeauration. From a synthetic point of view, it would be highly beneficial to engage the latter in cross coupling reactions. But the oxidative addition – reductive elimination cycle is not operant with gold(I) complexes. The best solution so far has been to set a concurrent photoredox cycle with the gold catalysis (dual catalysis). This ensures the formation of radical species which adds to gold(I) and the electronic shuttle between the Au(I)/Au(III) oxidation states. Nevertheless, this process is limited to aryldiazonium partners. Recently, we have evidenced a new dual cross coupling catalysis in which the photocatalytic step is not of photoredox nature but consists of an energy transfer. This type of pathway opens important synthetic perspectives notably in terms of new possible partners that we want to explore in the LuxOr project. Mechanistic issues will be also examined in great details relying on advanced photophysical studies, NMR analyses under illumination and DFT/TD-DFT modeling.

Project coordination

Louis FENSTERBANK (Institut Parisien de Chimie Moléculaire)

The author of this summary is the project coordinator, who is responsible for the content of this summary. The ANR declines any responsibility as for its contents.

Partner

IPCM Institut Parisien de Chimie Moléculaire
PASTEUR Processus d'Activation Sélectif par Transfert d'Energie Uni-électronique ou Radiatif
LiNC LILLE NEUROSCIENCE ET COGNITION

Help of the ANR 528,952 euros
Beginning and duration of the scientific project: December 2020 - 48 Months

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